Results 91 to 100 of about 97,688 (273)
The Stop-Signal Task - Cars aims to measure behavioral inhibition by having the child inhibit their reaction in response to a quickly appearing signal.
Leiden Consortium on Individual Development
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Time-estimation task with interspersed stop-signal trials.
, 2013 The tactile time-estimation task included three conditions (control, easy, hard) with different response-window adaptations leading to different error-rates (see text for details). In the randomly assigned stop-signal trials prior to response execution a
Markus Ullsperger (341551) +2 more
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Neural Mechanisms of Inhibitory Response in a Battlefield Scenario: a Simultaneous FMRI-EEG Study
Frontiers in Human Neuroscience, 2016 The stop-signal paradigm has been widely adopted as a way to parametrically quantify the response inhibition process. To evaluate inhibitory function in realistic environmental settings, the current study compared stop-signal responses in two different ...
Li-Wei eKo +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Infant Stop Signal Anticipation Task
The Stop Signal Anticipation task is adopted from Zandbelt and Vink (Vink et al., 2014, Zandbelt et al., 2008) and is also used as MRI task in the YOUth Child and Adolescent cohort. The Stop Signal Anticipation task measures response inhibition, which is
Youth of Utrecht
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Stop-signal anticipation task - functional MRI
Stop-signal anticipation task - functional MRI consists of a functional Magnetic Resonance Imaging (fMRI) scan that was acquired while subjects performed the Stop-signal anticipation (inhibition) experiment. The task aims to measure performance and brain
Youth of Utrecht
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Neural correlates of enhanced response inhibition in the aftermath of stress
NeuroImage, 2020 Life stress has been shown to impact cognitive functions, including inhibitory control. However, the immediate effects of acute stress on inhibitory control and the underlying neural mechanisms remain unclear.
Jingjing Chang +3 more
doaj +1 more source