Results 71 to 80 of about 97,688 (273)

Alpha- and beta-band oscillations subserve different processes in reactive control of limb movements

open access: yesFrontiers in Behavioral Neuroscience, 2014
The capacity to rapidly suppress a behavioral act in response to sudden instruction to stop is a key cognitive function. This function, called reactive control, is tested in experimental settings using the stop signal task, which requires subjects to ...
Pierpaolo ePani   +5 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Exploring stop signal reaction time over two sessions of the anticipatory response inhibition task [PDF]

open access: yes, 2022
Various behavioural tasks measure response inhibition encompassing the ability to cancel unwanted actions, evaluated via stop signal reaction time (SSRT).
McDonald, Hayley J.   +5 more
core   +1 more source

Release the BEESTS: Bayesian Estimation of Ex-Gaussian STop-Signal Reaction Time Distributions

open access: yesFrontiers in Psychology, 2013
The stop-signal paradigm is frequently used to study response inhibition. Inthis paradigm, participants perform a two-choice response time task wherethe primary task is occasionally interrupted by a stop-signal that promptsparticipants to withhold their ...
Dora eMatzke   +5 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Behavioral results ToM and stop-signal task for both groups.

open access: yes, 2013
Behavioral results ToM and stop-signal task for both groups.
Lisette van der Meer (144354)   +3 more
core   +1 more source

The Stop-Signal Paradigm

open access: yes, 2018
Response inhibition—the ability to stop responses that are no longer appropriate—is frequently studied with the stop‐signal paradigm. In the stop‐signal paradigm, participants perform a choice response time task that is occasionally interrupted by a stop
Frederick Verbruggen   +5 more
core   +2 more sources

Event-related potentials for post-error and post-conflict slowing. [PDF]

open access: yesPLoS ONE, 2014
In a reaction time task, people typically slow down following an error or conflict, each called post-error slowing (PES) and post-conflict slowing (PCS). Despite many studies of the cognitive mechanisms, the neural responses of PES and PCS continue to be
Andrew Chang   +3 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Microsaccade production during saccade cancelation in a stop-signal task

open access: yesVision Research, 2016
We obtained behavioral data to evaluate two alternative hypotheses about the neural mechanisms of gaze control. The "fixation" hypothesis states that neurons in rostral superior colliculus (SC) enforce fixation of gaze. The "microsaccade" hypothesis states that neurons in rostral SC encode microsaccades rather than fixation per se.
David C, Godlove, Jeffrey D, Schall
openaire   +2 more sources

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