Results 61 to 70 of about 97,688 (273)

Trial structure of the stop signal and Stroop task.

open access: yes, 2013
Example of a trial sequence in stop signal task (b) that parallels that in the Stroop task (a). In the Stroop task, color words that are printed in a color different from what the word says represent incongruent (I) trials; otherwise, they are congruent (
Olivia M. Hendrick (361137)   +3 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

The interplay between selective and nonselective inhibition during single word production. [PDF]

open access: yesPLoS ONE, 2018
The present study investigated the interplay between selective inhibition (the ability to suppress specific competing responses) and nonselective inhibition (the ability to suppress any inappropriate response) during single word production.
Ruben D Vromans, Suzanne R Jongman
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Stop signal task and trial structure.

open access: yes, 2014
(a) Stop signal paradigm. In “go” trials (∼75%), observers responded to the go signal (a circle), and in “stop” trials (∼25%), they had to withhold the response when they saw the stop signal (an X).
Chien-Chung Chen (283521)   +3 more
core   +1 more source

Response inhibition on the stop signal task improves during cardiac contraction. [PDF]

open access: yesSci Rep, 2018
Motor actions can be facilitated or hindered by psychophysiological states of readiness, to guide rapid adaptive action. Cardiovascular arousal is communicated by cardiac signals conveying the timing and strength of individual heartbeats. Here, we tested how these interoceptive signals facilitate control of motor impulsivity.
Rae CL   +8 more
europepmc   +6 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Validation of a Bayesian Adaptive Estimation Technique in the Stop-Signal Task

open access: yesPLOS ONE, 2016
The Stop Signal Task (SST), a commonly used measure of response inhibition, uses standard psychophysical methods to gain an estimate of the time needed to withhold a prepotent response. Under some circumstances, conventional forms of the SST are impractical to use because of the large number of trials necessary to gain a reliable estimate of the speed ...
Evan J Livesey, David J Livesey
openaire   +4 more sources

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