Results 51 to 60 of about 270,897 (278)
Ribosome signatures aid bacterial translation initiation site identification [PDF]
, 2017 Background: While methods for annotation of genes are increasingly reliable, the exact identification of translation initiation sites remains a challenging problem.
Chyżyńska, Katarzyna +5 more
core +2 more sources
Mitochondrial DNA. Part B. Resources, 2019 The Paracheirodon axelrodi is an important freshwater fish in the Amazon basin of South America, more expensive than Paracheirodon innesi. Here, we describe the complete 17,100 base pair (bp) mitochondrial genome of Paracheirodon axelrodi mohavensis. The
Yifan Liu +5 more
doaj +1 more source
The kinetic mechanism of bacterial ribosome recycling. [PDF]
, 2017 Bacterial ribosome recycling requires breakdown of the post-termination complex (PoTC), comprising a messenger RNA (mRNA) and an uncharged transfer RNA (tRNA) cognate to the terminal mRNA codon bound to the 70S ribosome.
Chen, Yuanwei +3 more
core +2 more sources
New insights into stop codon recognition by eRF1 [PDF]
Nucleic Acids Research, 2015 In eukaryotes, translation termination is performed by eRF1, which recognizes stop codons via its N-terminal domain. Many previous studies based on point mutagenesis, cross-linking experiments or eRF1 chimeras have investigated the mechanism by which the stop signal is decoded by eRF1.
Blanchet, Sandra +6 more
openaire +2 more sources
Mitochondrial DNA. Part B. Resources, 2019 We report the complete mitogenome of Hydrophis cyanocinctus, which is 17,750 bp in size and includes 13 protein-coding (PCGs), 2 rRNA genes, 22 tRNA genes, and 2 control regions. PCGs, with 13 genes, is 11,427 bp in length.
Qingbo Qiu +5 more
doaj +1 more source
Translation termination depends on the sequential ribosomal entry of eRF1 and eRF3.
, 2019 Translation termination requires eRF1 and eRF3 for polypeptide-and tRNA-release on stop codons. Additionally, Dbp5/DDX19 and Rli1/ABCE1 are required; however, their function in this process is currently unknown.
Beissel , C. +5 more
core +1 more source
The Jackprot Simulation Couples Mutation Rate with Natural Selection to Illustrate How Protein Evolution Is Not Random [PDF]
, 2011 Protein evolution is not a random process. Views which attribute randomness to molecular change, deleterious nature to single-gene mutations, insufficient geological time, or population size for molecular improvements to occur, or invoke “design ...
Bai, Chunyan Y. +2 more
core +2 more sources
Stop codon suppression via inhibition of eRF1 expression [PDF]
RNA, 2003 In humans, recognition of a stop codon by protein release factor eRF1 leads to release of the nascent peptide from the ribosome. Although efficient eRF1 activity is usually desirable, numerous pathologies result from eRF1 recognition of premature stop mutations in essential genes.
Jason, Carnes +3 more
openaire +2 more sources
Mitochondrial DNA. Part B. Resources, 2020 In this study, we sequenced the mitochondrial genome of Perlesta teaysia. The complete mitochondrial genome was 16,023 bp in length, including 37 typical genes and a control region. The overall nucleotide composition was biased toward the A/T nucleotides.
Sijin Chen +4 more
doaj +1 more source
Role of Premature Stop Codons in Bacterial Evolution [PDF]
Journal of Bacteriology, 2008 ABSTRACT When the stop codons TGA, TAA, and TAG are found in the second and third reading frames of a protein-encoding gene, they are considered premature stop codons (PSC). Deinococcus radiodurans disproportionately favored TGA more than the other two triplets as a PSC. The TGA triplet was also found more
Tit-Yee, Wong +5 more
openaire +2 more sources