Results 161 to 170 of about 815,824 (234)

The mRNA architecture of the translation termination site primes programmed stop codon readthrough events in <i>Drosophila</i>. [PDF]

RNA Biol
Kansara L, Wolfstetter G, Wintermayr D, Alexopoulos I, Escos A, Friedländer M, Engström Y.   +6 more
europepmc   +1 more source

MyD88‐Family Adaptors: Compartmentalised Signalling and Non‐Immune Functions

Immunology, EarlyView.
MyD88‐family adaptors coordinate receptor‐ and compartment‐specific innate immune signalling across plasma membrane and endosomal pathways. At the plasma membrane, TIRAP/MAL supports MyD88‐dependent signalling downstream of TLR2 and TLR4, whereas endosomal TLR7, TLR8 and TLR9 recruit MyD88 directly.
Seshu Vardhan Pothabathula, Saurabh Mishra, Pugazhendhi Kannan, Annette Bellar, Amy Attaway, Nicole Welch, Srinivasan Dasarathy   +6 more
wiley   +1 more source

Recoding by N¹-methylpseudouridine guides rational mRNA vaccine design. [PDF]

Nat Commun
Poulis P, Robecchi G, Kurochkina AO, Felletti M, Rodnina MV.   +4 more
europepmc   +1 more source

RING E3 ligase SNIPER8 functions redundantly with three close homologs to regulate the turnover of transcriptional co‐repressor TPR1

Journal of Integrative Plant Biology, EarlyView.
The Arabidopsis E3 ligase SNIPER8 negatively regulates immunity by promoting ubiquitination and proteasomal degradation of the transcriptional corepressor TOPLESS‐RELATED1, limiting excessive immune responses, maintaining immune homeostasis, and balancing defense activation and normal plant growth.
Xueru Liu, Paul Kapos, Zhongshou Wu, Yujun Peng, Meixuezi Tong, Asana Khajavi, Yan Huang, Yuelin Zhang, Xin Li   +8 more
wiley   +1 more source

Synthetic Biology Strategies for the Development of Live Attenuated Influenza Viruses: Recent Advances and Applications. [PDF]

Viruses
Yang K, Yang G, Xia Y, Ou X.
europepmc   +1 more source

SlBPC1 regulates fruit elongation by directly repressing SlOFP2/SlOFP21 and SUN expression in tomato

Journal of Integrative Plant Biology, EarlyView.
In tomato, switching off the transcription factor gene SlBPC1 leads to longer fruits by altering cell division patterns during early fruit development. The SlBPC1 regulatory pathway includes the SlOFP2, SlOFP21, and SUN genes, offering valuable targets for breeding tomatoes with market‐preferred shapes.
Sunan Gao, Long Cui, Licheng Xiao, Rong Huang, Jing Wei, Chunrui Chen, Wenran Su, Jiajun Ran, Lei Song, Jingyi Li, Taotao Wang, Zonglie Hong, Zhibiao Ye, Jie Ye, Junhong Zhang   +14 more
wiley   +1 more source

Nonsense-Mediated Decay mRNA Quality Control System Is Essential for Root Development and Efficient Root Nodule Symbiosis in Medicago truncatula. [PDF]

Plant Cell Environ
Biró JB, Péter C, Domonkos Á, Hegedűs Z, Lakatos L, Rana D, Gyula P, Silhavy D, Kaló P.   +8 more
europepmc   +1 more source

A NAC–MYB–cysteine regulatory module enhances drought and salt tolerance in soybean

Journal of Integrative Plant Biology, EarlyView.
In the GmNAC3—GmMYB60—GmCYS20 module, GmNAC3 represses the transcription factor gene GmMYB60 and GmMYB60 suppresses the cysteine biosynthetic gene GmCYS20. GmCYS20‐mediated cysteine metabolism feeds back to limit GmMYB60 activity. This transcription—metabolism circuit enhances stress tolerance and offers breeding targets for resilient soybean ...
Nannan Zhang, Jiale Liu, Wenhuan Lv, Yanting Li, Yuanwen Zheng, Qi Shi, Fangguo Chang, Hu Zhang, Shihao Jia, Jiale Cui, Qican Cheng, Muqadas Aleem, Aisha Almakas, Tuanjie Zhao, Jianying Feng, Jinming Zhao   +15 more
wiley   +1 more source

Experimental and modeling demonstration of stronger population suppression by gene drive targeting doublesex from dominant female-sterile resistance alleles. [PDF]

Nat Commun
Chen W, Wang Z, Champer J.
europepmc   +1 more source

Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation?

Journal of Periodontal Research, EarlyView.
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos, Magda Feres, William V. Giannobile, Hatice Hasturk, Egija Zaura   +4 more
wiley   +1 more source