Results 171 to 180 of about 815,824 (234)

Engineering suppressor tRNAs for effective treatment of Duchenne muscular dystrophy. [PDF]

Sci Adv
Oury J, Chen YH, McFarland S, Jewel D, Wen J, Pasricha T, Villaseñor S, Mannheim W, Rose V, Zheng S, Thanigai Arasu GS, Calhoun M, Dilts A, Montminy M, Strozewski N, Thakur N, Kaplan PL, Eimon PM, Coller J, Lodish H.   +19 more
europepmc   +1 more source

microRNA‐mediated control of cell fate specification and patterning in Marchantia polymorpha

New Phytologist, EarlyView.
The gemma developmental program in Marchantia polymorpha is coordinated by MpMIR166‐mediated repression of MpC3HDZ and auxin homeostasis. Summary MicroRNAs (miRNAs) are small non‐coding RNA molecules essential for growth and development in eukaryotes. In plants, the master gene DICER‐LIKE 1 (DCL1) catalyzes the biogenesis of miRNAs by processing double‐
Adolfo Aguilar‐Cruz, Eduardo Flores‐Sandoval, Ye Xu, Yu Yu, Ximena Gutiérrez‐Ramos, Cristian Y. González‐Rangel, Omar Oltehua‐López, Ana E. Dorantes‐Acosta, Joshua T. Trujillo, Hirotaka Kato, Kimitsune Ishizaki, Rebecca A. Mosher, Liam Dolan, Xuemei Chen, Daniel Grimanelli, Jim Haseloff, John L. Bowman, Mario A. Arteaga‐Vazquez   +17 more
wiley   +1 more source

The role of RNA modifications in cancer translational control. [PDF]

RNA Biol
Joy M, Cleynen A, Shirokikh NE.
europepmc   +1 more source

Jasmonate biosynthesis regulates key events in barley vegetative and reproductive development

New Phytologist, EarlyView.
Generation and general phenotypes of hvaoc mutants. Summary Cereal grain is a global food staple. Filial tissues in grain, such as the embryo and endosperm, grow embedded in the maternal ovule and surrounding ovary wall. Maternal tissues provide nutrition and protection but are progressively reduced and degraded as filial tissues expand, driving grain ...
Jian Luo, Linsan Liu, Xiujuan Yang, Olivia Doolan, Tanicha Duangta, Emily Lyon, Jonathan Griffin, Jennifer Shoesmith, Wenhao Wu, Ruth Hamilton, Mirjam Nuter, Mikah Katay‐Fodor, Neil Bricklebank, Nicola Aberdein, Guoping Zhang, Colin Turnbull, Matthew R. Tucker, Sarah M. McKim   +17 more
wiley   +1 more source

Novel examples of NMD escape through alternative intronic polyadenylation. [PDF]

NAR Genom Bioinform
Vlasenok M, Kuznetsova A, Skvortsov DA, Dontsova OA, Pervouchine DD.   +4 more
europepmc   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Natural and CRISPR/Cas9 Editing Variations of Dual‐uORFs Synergistically Increase the Nutritional Value of Silage Maize Feed

Plant Biotechnology Journal, EarlyView.
ABSTRACT The precise enhancement of nutritional quality in silage maize is a core strategy for increasing livestock production efficiency. Through evolutionary analysis of multiple plant species, we identified two functionally synergistic upstream open reading frames (uORF1 and uORF2) within the 5′ untranslated region of the gene encoding GDP‐L ...
Jing Zhou, Xi Wang, Yajing Zhang, Xinhao Luo, Shuyao Quan, Jie Ji, Lixue Sun, Xinyang Chen, Jin Chen, Jianbo Cheng, Jun Fan, Changsheng Li, Beijiu Cheng, Xiaoyu Li   +13 more
wiley   +1 more source

Signatures of nonsense-mediated mRNA decay but no evidence for transcriptional adaptation associated with protein-truncating variants in wild yeast diploids. [PDF]

Mol Biol Evol
Marszałek M, Babik W, Korona R, Tomala K.   +3 more
europepmc   +1 more source

HvPHO1 Controls a Glucose 1‐Phosphate–SnRK1 Signalling Module That Coordinates Starch Accumulation in Barley Endosperm

Plant Biotechnology Journal, EarlyView.
ABSTRACT Developing barley grains must balance the use of imported sucrose between soluble sugars and storage starch, but how this balance is controlled remains unclear. Here we show that loss of the plastidial α‐glucan phosphorylase HvPHO1 causes starch and soluble sugars to accumulate concurrently in barley grains.
Yulong Li, Yujia Chen, Jing Liu, Ping Yang, Guangqi Gao, Carlos Guzmán, Qiang Xu, Yazhou Zhang, Yanlin Liu, Pengfei Qi, Mei Deng, Shoufen Dai, Jian Ma, Guoyue Chen, Jirui Wang, Youliang Zheng, Yuming Wei, Qiantao Jiang   +17 more
wiley   +1 more source

Genus- and host-associated codon usage bias patterns in coronavirus spike genes. [PDF]

PLoS One
Chew JJ, Ng CH.
europepmc   +1 more source