Results 71 to 80 of about 127,164 (309)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Exercise Strategies for American Exotic Options under Ambiguity [PDF]
We analyze several exotic options of American style in a multiple prior setting and study the optimal exercise strategy from the perspective of an ambiguity averse buyer in a discrete time model of Cox–Ross–Rubinstein style.
Tatjana Chudjakow, Jörg Vorbrink
core
Remote Sensing, 2018 We present a new method for real-time runway detection embedded in synthetic vision and an ROI (Region of Interest) based level set method. A virtual runway from synthetic vision provides a rough region of an infrared runway.
Changjiang Liu, Irene Cheng, Anup Basu
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Exercise strategies for American exotic options under ambiguity
, 2009 Chudjakow T, Vorbrink J. Exercise strategies for American exotic options under ambiguity. Working Papers. Institute of Mathematical Economics. Vol 421.
Chudjakow, Tatjana, Vorbrink, Jörg
core +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Stopping rules and tactics for processes indexed by a directed set
, 1981 A new notion of tactic for processes indexed by a directed set is introduced. The main theorem, giving conditions under which tactics can be mapped on stopping times on the line, is applied to reduce some optimal stopping problems in the plane to the ...
Sucheston, Louis, Krengel, Ulrich
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Representations for optimal stopping under dynamic monetary utility functionals [PDF]
In this paper we consider the optimal stopping problem for general dynamic monetary utility functionals. Sufficient conditions for the Bellman principle and the existence of optimal stopping times are provided.
Volker Krätschmer, John Schoenmakers
core