Results 41 to 50 of about 49,874 (298)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Characterization of time-consistent sets of measures in finite trees [PDF]
, 2010 Bier M. Characterization of time-consistent sets of measures in finite trees. Working Papers. Institute of Mathematical Economics. Vol 434. Bielefeld: Universität Bielefeld; 2010.In this paper we give an alternative characterization for time-consistent ...
Bier, Monika
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
PLoS ONE, 2012 BackgroundThe current stopping rule for peginterferon/ribavirin therapy in hepatitis C virus genotype-1 (HCV-1) patients is based on an early virological response (EVR, defined as >2 log(10) viral reduction at treatment week 12).
Ming-Lung Yu +11 more
doaj +1 more source
When Goal-Setting Forges Ahead but Stops Short [PDF]
SSRN Electronic Journal, 2020 In this study, we use at scale randomized control trial among 18,000 secondary students in 181 schools in Tanzania (Zanzibar) to examine the effects of personal best goal-settings on students’ academic performance. We also offer non-financial rewards to students to meet the goals they set.
Islam, Asad +5 more
openaire +4 more sources
Superharmonic fuzzy sets on recurrent sets in dynamic fuzzy systems [PDF]
, 1999 We analyse P-superharmonic fuzzy sets on recurrent sets in dynamic fuzzy systems and we derive a simple estimation for the fuzzy sets.
Yoshida, Y.
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Exercise strategies for American exotic options under ambiguity [PDF]
, 2009 Chudjakow T, Vorbrink J. Exercise strategies for American exotic options under ambiguity. Working Papers. Institute of Mathematical Economics. Vol 421.
Chudjakow, Tatjana, Vorbrink, Jörg
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source