Results 61 to 70 of about 30,948 (306)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

STORE ATMOSPHERE DALAM MENINGKATKAN KEPUTUSAN PEMBELIAN PADA RESTORAN KAPAL JODOH BATU MARMAR PAMEKASAN

Al Iqtishod, 2020
The purpose of this study was conducted with the main objective to be achieved, namely to determine the store atmosphere and purchase decisions at the Jodoh Tamberu Alet Ship Restaurant, Batu Marmar District.
Nuer Riskiyah, Aang Kunaifi, Matnin Matnin, Qaiyim Asyari   +3 more
doaj   +1 more source

The Effect of the Atmosphere and Store Layout and Web Design, Online Impulse Buying Behavior of Customers [PDF]

‫مدیریت بازرگانی, 2017
The aim of this study was to evaluate the effect of the atmosphere and store layout and web design, online impulse buying behavior of customers is that impulsive behavior, impulsive behavior and shopping pleasure it is considered as a mediator.
Ali Esmaeelzadeh, Hafez Amraee, Sara Gholipoor, Arash Moghadam   +3 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Retail Atmospherics and In‐Store Nonverbal Cues: An Introduction

Psychology & Marketing, 2014
ABSTRACTCustomers' in‐store experiences are having a profound impact on their shopping behavior. In this special issue, two key variables are highlighted: the retail environment and role of nonverbal cues. The eight papers in this special issue present numerous cutting edge issues in these two research domains.
Grewal, D, Roggeveen, A, Puccinelli, N, Spence, C   +3 more
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Pengaruh Store Atmosphere Wakai Terhadap Customer Experience [PDF]

, 2016
Retailing di Indonesia telah menunjukan peningkatan dan persaingan yang begitu kompetitif. Usaha retail membutuhkan lebih dari sekedar harga murah dan produk yang inovatif tetapi harus fokus pada pengalaman konsumen.
Yuliesta, Linda
core  

STORES ATMOSPHERE AND PROMOTION ON CUSTOMER SATISFACTION AND ITS IMPACT ON CONSUMER LOYALTY

Trikonomika, 2019
Le Delice Cafe and Bakery is a business that engaged in the culinary business. Analysis of data used is using path analysis (path analysis), multiple correlation, and coefficients of determination.
Popo Suryana, Mochammad Rifal Haryadi
doaj   +1 more source

THE ROLE OF STORE LOCATION AND STORE ATMOSPHERE ON CUSTOMER LOYALTY

Multifinance
The coffee shop business in Indonesia has become a trend in recent years. Osiris Coffee is a business unit that provides customers with services and products. Over the last six months, Osiris Coffee has experienced a decline in the number of customers, which is believed to be due to the coffee shop's less strategic location and atmospheric store, which
Abdul Azis, Nurul Hermina
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source