Results 51 to 60 of about 2,257,308 (283)

Strain gradient and electric field gradient effects in piezoelectric cantilever beams

Journal of the Mechanical Behavior of Materials, 2015
A piezoelectric beam model with strain gradient and electric gradient effects is proposed. An energy variational principle with strain, strain gradient, electric field, and electric field gradient considered as independent variables is postulated to ...
Yue Yanmei, Xu Kaiyu, Aifantis Elias C.
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Back stress strengthening and strain hardening in gradient structure [PDF]

, 2016
We report significant back stress strengthening and strain hardening in gradient structured (GS) interstitial-free (IF) steel. Back stress is long-range stress caused by the pileup of geometrically necessary dislocations (GNDs).
Pan Y, Yang MX(杨沐鑫), Zhu YT, Wu, XL (reprint author), Chinese Acad Sci, State Key Lab Nonlinear Mech, Inst Mech, 15 Beisihuan West Rd, Beijing 100190, Peoples R China., Yuan FP(袁福平), Wu XL(武晓雷)   +5 more
core   +1 more source

Flexoelectricity in oxide thin films

Journal of Advanced Dielectrics
Flexoelectric effect describes the electromechanical coupling between the strain gradient and its internal polarization in all dielectrics. Despite this universality, the resulting flexoelectric field remains small at the macroscopic level.
Guoyang Shen, Renhong Liang, Zhiguo Wang, Zhiyong Liu, Longlong Shu   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Investigation of continuum damage mechanics model without element size sensitivity

Nihon Kikai Gakkai ronbunshu, 2017
A discontinuous material behavior such as ductile fracture and fatigue failure is predicted actively in various fields by FEM. There is continuum damage mechanics as a method to evaluate the discontinuous material behavior in a framework of continuum ...
Satoshi HIROSE, Yutaka TOI
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A Review on Heterogeneous Nanostructures: A Strategy for Superior Mechanical Properties in Metals

Metals, 2019
Generally, strength and ductility are mutually exclusive in homogeneous metals. Nanostructured metals can have much higher strength when compared to their coarse-grained counterparts, while simple microstructure refinement to nanoscale generally results ...
Yan Ma, Muxin Yang, Fuping Yuan, Xiaolei Wu   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source