Results 51 to 60 of about 48,906 (308)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

A new hardening law for strain gradient plasticity

, 2000
A new hardening law of the strain gradient theory is proposed in this paper, which retains the essential structure of the incremental version of conventional J(2) deformation theory and obeys thermodynamic restrictions.
Chen, SH (reprint author), Chinese Acad Sci, Inst Mech, LNM, Beijing 100080, Peoples R China., 陈少华, 王自强   +2 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Mechanical Properties and Strain Hardening Behaviour of Magnesium Alloys and Composites

, 2010
Selected magnesium alloys and composites with magnesium alloy matrix were deformed at temperatures between room temperature and 300 °C at constant strain rate. The testing temperature influences significantly the deformation behaviour of the al/loys. The
Pavel Lukac, Zuzanka Trojanova
core   +1 more source

Effect of fiber orientation and specimen thickness on the tensile response of strain hardening UHPFRC mixes with reduced Embodied Energy [PDF]

, 2017
Ultra-High Performance Fiber Reinforced Concretes (UHPFRC) have demonstrated their potential to contain the explosion of maintenance costs (Economy and Environment) for civil engineering structures, due to their extremely low permeability associated with
Hajiesmaeili, Amir, Amir Hajiesmaeili, Denarié, Emmanuel, Emmanuel Denarié   +3 more
core   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Fractional derivative-based normalized viscoelastic model of strain-hardening clays

Frontiers in Materials
Introduction: The stress-strain relationship of clays characterized by strain hardening exhibits varying curves under different confining pressures and dry densities.Methods: Considering the viscoelastic properties of clays, a normalized viscoelastic ...
Yin Tang, Peng Wang, Peng Wang, Peng Ren, Hua Zhang   +4 more
doaj   +1 more source

Some aspects on geometric and matrix work-hardening characteristics of sintered cold forged copper alloy preforms [PDF]

Materials Research, 2013
Powder metallurgy (P/M) material subjected to plastic deformation results into densification, however the extended deformation would not only enhance the densification also supplements the strain hardening.
A Rajeshkannan, Devi S Rengamani, Alok Sharma   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source