Results 61 to 70 of about 1,250,898 (288)

Strain hardening by sediment transport

open access: yesPhysical Review Research, 2022
The critical fluid-shear stress for the onset of sediment transport, θ_{c}, varies with the history of applied shear. This effect has been primarily attributed to compaction; the role of shear jamming is less explored.
Fernando D. Cúñez   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Metodologias de investigação para metais utilizados em conformação plástica [PDF]

open access: yes, 2007
Doutoramento em Engenharia MecânicaNeste trabalho apresentam-se novas metodologias experimentais de análise dos mecanismos físicos que controlam a formabilidade das ligas de Al-Mg e o encruamento transitório em metais unifásicos. Para as ligas de Al-Mg a
Vincze, Gabriela Tamara
core  

Some aspects on geometric and matrix work-hardening characteristics of sintered cold forged copper alloy preforms [PDF]

open access: yesMaterials Research, 2013
Powder metallurgy (P/M) material subjected to plastic deformation results into densification, however the extended deformation would not only enhance the densification also supplements the strain hardening.
A Rajeshkannan   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Constitutive modeling for the flow stress behaviors of alloys based on variable order fractional derivatives

open access: yesMaterials Research Express, 2022
During hot working, alloys may experience three kinds of flow stress behaviors, including strain hardening, strain softening, or steady flow, because of the competition of work hardening and thermal softening. Modelling the flow stress behaviors plays an
Ruifan Meng, Liu Cao, Qindan Zhang
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Strain hardening in Fe-16Mn-10Al-0.86C-5Ni high specific strength steel

open access: yes, 2016
We report a detailed study of the strain hardening behavior of a Fe-16Mn-10Al-0.86C-5Ni (weight percent) high specific strength (i.e. yield strength-to-mass density ratio) steel (HSSS) during uniaxial tensile deformation.
Xie QG   +5 more
core   +1 more source

Evidence of Strain Hardening in DNA Gels

open access: yesMacromolecules, 2010
Strain hardening observed in many biological gels is nature's defense against the external forces to protect the tissue integrity. Here, we show that double-stranded (ds) DNA gels also stiffen as they arestrained.ChemicalDNAgelswerepreparedbysolutioncross-linkingofds-DNA(about2000basepairs long) using the cross-linker ethylene glycol diglycidyl ether ...
Orakdogen, Nermin   +2 more
openaire   +2 more sources

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