Results 71 to 80 of about 48,906 (308)

SOME ASPECTS OF FRICTION AND ANISOTROPIC RATIOS ON THE WORK HARDENING BEHAVIOR IN THE UPSETTING TESTS [PDF]

Proceedings on Engineering Sciences
Metal upsetting is a primary mechanical working operation to reduce the cross-section of the billets, and there are few challenges that are to be solved.
Harikrishna Ch , Varun Chandra Samudrala , Murahari kolli , Srinivasaraju Perecherla , N Malleswararao Battina , Srinivasarao Gajula   +5 more
doaj   +1 more source

Nanoscale Strain-Hardening of Keratin Fibres

PLoS ONE, 2012
Mammalian appendages such as hair, quill and wool have a unique structure composed of a cuticle, a cortex and a medulla. The cortex, responsible for the mechanical properties of the fibers, is an assemblage of spindle-shaped keratinized cells bound together by a lipid/protein sandwich called the cell membrane complex. Each cell is itself an assembly of
Patrick Fortier, Sandy Suei, Laurent Kreplak   +2 more
openaire   +4 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Evidence of Strain Hardening in DNA Gels

Macromolecules, 2010
Strain hardening observed in many biological gels is nature's defense against the external forces to protect the tissue integrity. Here, we show that double-stranded (ds) DNA gels also stiffen as they arestrained.ChemicalDNAgelswerepreparedbysolutioncross-linkingofds-DNA(about2000basepairs long) using the cross-linker ethylene glycol diglycidyl ether ...
Orakdogen, Nermin, Erman, Burak, Okay, Oguz   +2 more
openaire   +2 more sources

Analysis of strain hardening of ADI at isothermal hardening temperatures

Bulletin of the National Technical University «KhPI» Series: New solutions in modern technologies, 2020
The effect of isothermal hardening temperature on the mechanical properties of ADI materials is investigated. The heat treatment of the test samples consisted of the heating above the temperature of transformation of the ferrite component in austenite and isothermal hardening at temperatures from 280 to 380 °C.
Gogaev, Kazbek, Podrezov, Yuriy, Voloshchenko, Sergey, Askerov, Mukafat Geibat ogly, Minakov, Nikolay, Lugоvskoy, Yuri   +5 more
openaire   +3 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Multi-stage strain-hardening behavior of dual-phase steels: A review

Journal of Materials Research and Technology
Regardless of the abundant studies that have been published on various characteristics of dual-phase (DP) steels, a comprehensive review paper on the strain-hardening behavior of such materials is still lacking.
Y. Najafi, Y. Mazaheri, Z. Delbari Ragheb, H. Daiy   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source