Results 71 to 80 of about 153,531 (299)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Evolution of entanglements during the response to a uniaxial deformation of lamellar triblock copolymers and polymer glasses

, 2010
Using coarse-grained molecular-dynamics simulations, a generic styrene-(block)-butadiene-(block)-styrene (SBS) triblock copolymer under lamellar conformation is used in order to investigate the mutual entanglement evolution when a structure of ...
Léonforte, F.
core   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

SOME ASPECTS OF FRICTION AND ANISOTROPIC RATIOS ON THE WORK HARDENING BEHAVIOR IN THE UPSETTING TESTS [PDF]

Proceedings on Engineering Sciences
Metal upsetting is a primary mechanical working operation to reduce the cross-section of the billets, and there are few challenges that are to be solved.
Harikrishna Ch , Varun Chandra Samudrala , Murahari kolli , Srinivasaraju Perecherla , N Malleswararao Battina , Srinivasarao Gajula   +5 more
doaj   +1 more source

Correlations Between Metallurgical Characterization Studies, Exploratory Mechanical Tests, and Continuum Mechanics Approaches to Constitutive Equations [PDF]

, 1983
Austenitic stainless steels, such as types 316 and 304, are widely used as pressure vessel materials in the temperature range of 425 to 650 C. Stainless steel specimens were tested to rupture at two different stress levels sigma and sigma 2 sigma 1 sigma
Moteff, J., Pugh, C. E., Swindeman, R. W.   +2 more
core   +1 more source

Stress-strain response and microstructural evolution of a FeMnCAl TWIP steel during tension-compression tests [PDF]

, 2016
© 2016. The stress-strain response of a Fe-17.5Mn-0.7C-2Al TWIP steel during cyclic loading has been investigated by means of tension-compression tests within the strain limits of ±2%, ±5% and ±10%. In addition, the microstructural evolution during the ±
Benito Páramo, José Antonio, Cabrera Marrero, José M., Calvo Muñoz, Jessica, Cobo Molina, Raúl   +3 more
core   +2 more sources

Nanoscale Strain-Hardening of Keratin Fibres

PLoS ONE, 2012
Mammalian appendages such as hair, quill and wool have a unique structure composed of a cuticle, a cortex and a medulla. The cortex, responsible for the mechanical properties of the fibers, is an assemblage of spindle-shaped keratinized cells bound together by a lipid/protein sandwich called the cell membrane complex. Each cell is itself an assembly of
Patrick Fortier, Sandy Suei, Laurent Kreplak   +2 more
openaire   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Multi-stage strain-hardening behavior of dual-phase steels: A review

Journal of Materials Research and Technology
Regardless of the abundant studies that have been published on various characteristics of dual-phase (DP) steels, a comprehensive review paper on the strain-hardening behavior of such materials is still lacking.
Y. Najafi, Y. Mazaheri, Z. Delbari Ragheb, H. Daiy   +3 more
doaj   +1 more source