Results 51 to 60 of about 25,125 (299)

Experimental study on low cycle fatigue behavior of TWIP steel under cyclic shear loading condition

Journal of Materials Research and Technology
This study investigated the low-cycle fatigue (LCF) behavior of Twinning induced plasticity (TWIP) steel based on the twin bridge shear specimen and cyclic shear loading condition.
Chen Jiaqi, Yang Yiming, Ren Qizhen, Qiu Yuliang, Yue Zhenming, Zhou Yiqi, Chu Xingrong   +6 more
doaj   +1 more source

Acquisition and Evaluation of Theoretical Forming Limit Diagram of Al 6061-T6 in Electrohydraulic Forming Process

Metals, 2019
The current study examines the forming limit diagram (FLD) of Al 6061-T6 during the electrohydraulic forming process based on the Marciniak–Kuczynski theory (M-K theory).
Min-A Woo, Woo-Jin Song, Beom-Soo Kang, Jeong Kim   +3 more
doaj   +1 more source

Anomalous Work Hardening Behavior of a Single Crystalline Co-Base Superalloy

Alloys, 2022
The defect evolution associated with an anomalous work hardening behavior of a single crystalline quaternary Co-Al-W-Ta superalloy at 950 °C was investigated by transmission electron microscopy.
Andreas Bezold, Nicklas Volz, Fei Xue, Mathias Göken, Steffen Neumeier   +4 more
doaj   +1 more source

An experimental investigation of the behaviour of steels over large temperature and strain rate ranges [PDF]

, 2013
During forging and machining manufacturing processes, the material is subject to large strains at high strain rates which provoke local heating and microstructural changes.
GERMAIN, Guénaël, HOR, Anis, LEBRUN, Jean-Lou, MOREL, Franck   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Martensite reversion and strain hardening of a 2304 lean duplex stainless steel subjected to cold rolling and isochronous annealing at low temperatures

Journal of Materials Research and Technology, 2022
Lean duplex stainless steels (LDSS) have a microstructure composed of ferrite and austenite phases. This microstructure provides good mechanical and corrosion resistances.
Renata Mangini Santos, Daniella Gomes Rodrigues, Maria Luiza Dias Santos, Dagoberto Brandão Santos   +3 more
doaj   +1 more source

High Strain Rate Hardening of Metallic Cellular Metamaterials

Journal of Dynamic Behavior of Materials
AbstractStrain rate hardening caused by the changed deformation mode is a fascinating phenomenon in cellular metamaterials where the material’s stiffness and energy absorption capabilities increase as the strain rate increases. This unique behaviour is attributed to a combination of micro-inertia effects, base material’s strain rate hardening and ...
N. Novak, M. Vesenjak, Z. Ren
openaire   +2 more sources

Cyclic J-integral using the linear matching method

, 2013
The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source