Results 101 to 110 of about 4,685,644 (340)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Dynamics of structural defects and plasticity: models and numerical implementation for dynamical problems [PDF]

, 2013
We report the plasticity model with explicit description of kinetics of the material defects (dislocations, grain boundaries). This method becomes especially effective for computation of the dynamical deformation of materials at high strain rates because
Borodin, Elijah N., Krasnikov, Vasily S., Mayer, Alexander F., Mayer, Polina N.   +3 more
core  

Microscopic Mechanism of Shear Bands in Amorphous Solids

, 2012
The fundamental instability responsible for the shear localization which results in shear bands in amorphous solids remains unknown despite enormous amount of research, both experimental and theoretical.
Dasgupta, Ratul, Hentschel, H. George E., Procaccia, Itamar   +2 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Overview of the theoretical relations between necking and strain localization criteria. [PDF]

, 2013
Many criteria have been developed during last decades to predict diffuse or localized necking and shear banding. The lack of confrontation of these models with each other on relevant applications makes their choice difficult for the designer.
ABED-MERAIM, Farid, ALTMEYER, Guillaume, BALAN, Tudor   +2 more
core   +3 more sources

Colloquium: The transport properties of graphene: An introduction

, 2010
An introduction to the transport properties of graphene combining experimental results and theoretical analysis is presented. In the theoretical description simple intuitive models are used to illustrate important points on the transport properties of ...
Abrikosov, A. A., Castro Neto, A. H., Ferry D. K., Fuhrer, M. S., Geim, A. K., Landau, L. D., Mahan, G. D., N. M. R. Peres, Nazarov, Y. V., Peierls, R., Poirier, W., Silvester, P. P., Slater, J. C., Ziman, J. M.   +13 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Strain dependence of the Mn anisotropy in ferromagnetic semiconductors observed by x-ray magnetic circular dichroism

, 2008
We demonstrate sensitivity of the Mn 3d valence states to strain in the ferromagnetic semiconductors (Ga,Mn)As and (Al,Ga,Mn)As, using x-ray magnetic circular dichroism (XMCD).
A. Shen, B. L. Gallagher, C. T. Foxon, E. Arenholz, G. van der Laan, K. W. Edmonds, N. R. S. Farley, R. P. Campion   +7 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source