Results 211 to 220 of about 44,419 (247)
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Autonomous Resolution Based on DNA Strand Displacement
2011We present a computing model based on the technique of DNA strand displacement which performs a chain of logical resolutions with logical formulae in conjunctive normal form. The model is enzymefree and autonomous. Each clause of a formula is encoded in a separate DNA molecule: propositions are encoded assigning a strand to each proposition p, and its ...
Alfonso Rodríguez-Patón +2 more
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Analog Computation by DNA Strand Displacement Circuits
ACS Synthetic Biology, 2016DNA circuits have been widely used to develop biological computing devices because of their high programmability and versatility. Here, we propose an architecture for the systematic construction of DNA circuits for analog computation based on DNA strand displacement.
Tianqi, Song +4 more
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Circular DNA Logic Gates with Strand Displacement
Langmuir, 2009Circular DNA logic gates were constructed on the basis of DNA three-way branch migration. In this logic system, circular DNA was used as a basic work unit and linear single-strand DNA was used as input and output signals. Making use of the circular structure, most of the DNA-specific recognition regions were designed in a single DNA ring.
Cheng, Zhang, Jing, Yang, Jin, Xu
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Connecting localized DNA strand displacement reactions
Nanoscale, 2015Design and characterization of a DNA-based localized amplification circuit which, upon tethering on a DNA origami platform, greatly accelerates the catalytic response.
Ismael Mullor, Ruiz +5 more
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Robustness of Localized DNA Strand Displacement Cascades
ACS Nano, 2014Colocalization can strongly alter the kinetics and efficiency of chemical processes. For instance, in DNA-templated synthesis unfavorable reactions are sped up by placing reactants into close proximity onto a DNA scaffold. In biochemistry, clustering of enzymes has been demonstrated to enhance the reaction flux through some enzymatic cascades.
Mario, Teichmann +2 more
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Performing DNA Strand Displacement with DNA Polymerase
2020Significant improvements to the dynamic DNA nano science have emerged in recent years, primarily due to the elaborate design of toehold-mediated DNA strand displacement (TMSD). However, it remains an ongoing challenge to design huge-scaled TMSD based sophisticated dynamic DNA structures without base-pair mismatching or unwanted secondary structures ...
Zhiyu Wang +4 more
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Efficient Multidriven Strand Displacement Reaction for Biosensing
Analytical ChemistryA key challenge for achieving high-efficient DNA strand displacement reaction (SDR) with existing technologies is the inferior kinetic performance due to the alternately cumbersome conjunction and dissociation of dsDNA. In this work, a novel multidriven SDR collaborated by toehold initiator, strand towing, and click chemistry is engineered.
Rui Zhang +4 more
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Cooperative Branch Migration: A Mechanism for Flexible Control of DNA Strand Displacement
ACS Nano, 2022, , Ting Wang
exaly
Leakless Polymerase-Dependent Strand Displacement Systems.
A grand challenge facing molecular programmers is the rational development of fast, robust, and isothermal architectures akin to "chemical central processing units" that can sense (bio-)chemical signals from their environment, perform complex computation, and orchestrate a physical response in situ.Derauf, Zoë Evelyn Mōhalakealoha +1 more
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