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An emergent understanding of strand displacement in RNA biology

Journal of Structural Biology, 2019
DNA and RNA are generally regarded as central molecules in molecular biology. Recent advancements in the field of DNA/RNA nanotechnology successfully used DNA/RNA as programmable molecules to construct molecular machines and nanostructures with predefined shapes and functions.
Fan, Hong, Petr, Šulc
openaire   +2 more sources

Performing DNA Strand Displacement with DNA Polymerase

2020
Significant improvements to the dynamic DNA nano science have emerged in recent years, primarily due to the elaborate design of toehold-mediated DNA strand displacement (TMSD). However, it remains an ongoing challenge to design huge-scaled TMSD based sophisticated dynamic DNA structures without base-pair mismatching or unwanted secondary structures ...
Zhiyu Wang   +4 more
openaire   +1 more source

Response of a Strand to Axial and Torsional Displacements

Journal of Mechanical Engineering Science, 1973
Taking advantage of geometric considerations the authors give explicit expressions for the determination of axial force, bending and twisting moments in the helical wires, and for the axial force and twisting moment in the core of a 7-wire strand subjected to axial and torsional displacements.
S. Machida, A. J. Durelli
openaire   +1 more source

Efficient Multidriven Strand Displacement Reaction for Biosensing

Analytical Chemistry
A key challenge for achieving high-efficient DNA strand displacement reaction (SDR) with existing technologies is the inferior kinetic performance due to the alternately cumbersome conjunction and dissociation of dsDNA. In this work, a novel multidriven SDR collaborated by toehold initiator, strand towing, and click chemistry is engineered.
Rui Zhang   +4 more
openaire   +2 more sources

Leakless Polymerase-Dependent Strand Displacement Systems.

A grand challenge facing molecular programmers is the rational development of fast, robust, and isothermal architectures akin to "chemical central processing units" that can sense (bio-)chemical signals from their environment, perform complex computation, and orchestrate a physical response in situ.
Derauf, Zoë Evelyn Mōhalakealoha   +1 more
openaire   +2 more sources

Encryption Algorithm Based on DNA Strand Displacement and DNA Sequence Operation

IEEE Transactions on Nanobioscience, 2021
Chengye Zou   +2 more
exaly  

Novel RNase H Inhibitors Blocking RNA-directed Strand Displacement DNA Synthesis by HIV-1 Reverse Transcriptase

Journal of Molecular Biology, 2022
Dongwei Kang   +2 more
exaly  

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