Results 71 to 80 of about 2,765 (281)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Human–AI Compass for Sustainable Art Museums: Navigating Opportunities and Challenges in Operations, Collections Management, and Visitor Engagement

open access: yesHeritage
This paper charts AI’s transformative path toward advancing sustainability within art museums, introducing a Human–AI compass as a conceptual framework for navigating its integration.
Charis Avlonitou   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Le métier d’enseignant : formation professionnelle et formation des talents

open access: yesRecherches en Éducation, 2010
The masterization process of initial teacher training, in Italy and in France, settles strong façon in the problem of links between teacher training and educational research. For us the monster crucial question is that a new compass is essential.
Umberto Margiotta
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Problem of EU’s Strategic Autonomy in the Space Sector under Contemporary Security Challenges [PDF]

open access: yesRomanian Journal of European Affairs
The article examines the issue of EU’s strategic autonomy in space, in the context of contemporary security challenges. Its aim is to analyse EU’s current space policy, its security dimension, and the role of its key instruments – technological ...
Olha Ivasechko   +4 more
doaj  

Rebranding the Capital Markets Union – Towards an Integrated Financial Ecosystem

open access: yesStrani pravni život
This paper examines the current state and future prospects of the EU’s Capital Markets Union within the context of ongoing economic challenges, including climate change, technological transformation, and geopolitical shifts.
Ivana Bajakić
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

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