Results 171 to 180 of about 1,539,111 (274)

Strategic decision making in live streaming e-commerce through tripartite evolutionary game analysis. [PDF]

PLoS One
Xu Y, Qi J, Kong J, Zhang W.
europepmc   +1 more source

QuantumIS: A Qualia Consciousness Awareness and Information Theory Quale Approach to Reducing Strategic Decision-Making Entropy. [PDF]

Entropy (Basel), 2019
Rodger JA.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Enhancing strategic decision-making in built asset management through BIM-Enabled asset information modelling (AIM) for public buildings in Ethiopia: A fuzzy-AHP analysis. [PDF]

Heliyon
Desbalo MT, Woldesenbet AK.
europepmc   +1 more source

Neural Basis of Strategic Decision Making. [PDF]

Trends Neurosci, 2016
Lee D, Seo H.
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Effective waste management in service industry: Fuzzy-based modelling approach for strategic decision-making. [PDF]

Waste Manag Res
Dinçer H, Yüksel S, Eti S, Gökalp Y, Mikhaylov A, Karpyn Z.   +5 more
europepmc   +1 more source

A resource of potential drug targets and strategic decision-making for obstructive sleep apnoea pharmacotherapy. [PDF]

Respirology, 2017
Horner RL, Grace KP, Wellman A.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Assessing cybersecurity risks and prioritizing top strategies In Vietnam's finance and banking system using strategic decision-making models-based neutrosophic sets and Z number. [PDF]

Heliyon
Nguyen PH, Pham TV, Nguyen LT, Pham HT, Nguyen TT, Vu TG.   +5 more
europepmc   +1 more source