Results 101 to 110 of about 812,510 (332)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Strategic Environmental Assessment of Land Transportation: An Application of DEA with Undesirable Output Approach [PDF]
, 2022 Chia‐Nan Wang +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Strategic environmental assessment in urban development Case study: (Zahedan city) [PDF]
علوم محیطی, 2018 Introduction: Environmental problems are one of the most important issues in major cities, metropolises and it is the result of confliction with the natural environment because urban development is necessarily associated with the domination of buildings,
Zohreh Fanni +2 more
doaj
Melbourne urban development: policy statement for EPBC Act referrals [PDF]
Actions considered under this policy include urban, commercial and light industrial developments and infrastructure directly servicing such development (roads, pipelines and other utilities).
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
STRATEGIC ENVIRONMENTAL ASSESSMENT OF THE ADJUSTMENT PROCESS OF THE CITY MASTERPLAN TO THE SARDINIAN REGIONAL LANDSCAPE PLAN: THE CASE OF CITY MASTERPLAN OF ALGHERO, SARDINIA (ITALY) [PDF]
Strategic Environmental Assessment (SEA) in the context of the enactment of the Directive 2001/42/CE is at the core of the adjustment process of provincial and city Masterplan to the Sardinian Regional Landscape Plan (RLP).
Cheti Pira, Federica Isola
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Multi-Criteria Optimal Planning for Energy Policies in CLP [PDF]
, 2014 In the policy making process a number of disparate and diverse issues such as economic development, environmental aspects, as well as the social acceptance of the policy, need to be considered.
Bragaglia, Stefano +5 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source