Results 111 to 120 of about 6,747,171 (335)
For Our Future: the 21st Century Higher Education Strategy and Plan for Wales [PDF]
, 2009 "The document is a new higher education strategy and plan for Wales. It builds upon and replaces Reaching Higher. The plan provides a response to the Jones Review of Higher Education in Wales which looked at the mission, purpose, role and funding of ...
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Vision 21: The NASA strategic plan [PDF]
The NASA Strategic Plan, Vision 21, is a living roadmap to the future to guide the men and women of the NASA team as they ensure U.S. leadership in space exploration and aeronautics research.
core +1 more source
Regional construction sector: sector implementation plan (SIP) [PDF]
, 2008 This Sector Implementation Plan (SIP) forms an integral part of the Regional Economic Strategy (RES), acting as a high level plan for the region’s construction sector, and providing an overview of the strategic actions and interventions which will ...
EMCBE
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Iowa Department of Cultural Affairs, Strategic Plan 2008-2011, 2008 [PDF]
, 2008 This report outlines the strategic plan for Iowa Department of Cultural Affairs, goals and ...
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
An assessment of implementation and evaluation phases of strategic plans in Iranian hospitals
SAGE Open Medicine, 2017 Objectives: To assess the implementation and evaluation phases of strategic plans in selected hospitals. Methods: We conducted a cross-sectional study of implementation and evaluation of strategic plan in 24 hospitals in 2015, using a questionnaire which
Jamil Sadeghifar +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Maximizing Foundation Effectiveness: Aligning Program Strategy, Organizational Capacity, Strategic Planning, and Performance Assessment to Achieve Success [PDF]
, 2008 This paper outlines a framework for increasing the philanthropic performance of an organization by focusing on strategic planning and development of tight logic models for the organization's programs.
Paul Connolly
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