Results 111 to 120 of about 1,521,389 (308)

Modern approaches to the immunotherapy of Clostridioides difficile

open access: yesЖурнал инфектологии
Clostridioides difficile is a leading cause of diarrhea and pseudomembranous colitis associated with antibiotic therapy. Hypervirulent strains of C. difficile, such as ribotype 027, have high mortality rates. Recurrent C. difficile infection is extremely
K. E. Popruga, V. V. Makarov
doaj   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Strategic Planning at Five World-Class Companies [PDF]

open access: yes, 1995
Most successful executives know that strategic planning offers the best way to deal with their changing world. Information is central to successful strategic planning.
Akers, Michael D., Porter, Grover L
core   +1 more source

Development of a Prediction Model for Progression Risk in High‐Grade Gliomas Based on Habitat Radiomics and Pathomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate the value of constructing models based on habitat radiomics and pathomics for predicting the risk of progression in high‐grade gliomas. Methods This study conducted a retrospective analysis of preoperative magnetic resonance (MR) images and pathological sections from 72 patients diagnosed with high‐grade gliomas (52 ...
Yuchen Zhu   +14 more
wiley   +1 more source

Cancer Research in 2030: A unique strategic planning process at a comprehensive cancer center. [PDF]

open access: yesPrev Oncol Epidemiol, 2023
Bank EM, Small EJ, Ashworth A, Hiatt RA.
europepmc   +1 more source

Systematisation of Corporate Planning [PDF]

open access: yes
The systematization of corporate planning is a subject that provokes the research interest due to the increased importance of strategic and long-term planning for the corporate development.
Lyudmila MIHAYLOVA
core  

Franklin County Justice Programs Unit Asset Inventory: Justice System Data Profile [PDF]

open access: yes, 2001
CRP used key informant interviews and a mail survey to develop an asset inventory and needs assessment for the Franklin County criminal justice system. In addition, CRP prepared an overview of data that describe trends and conditions in Franklin County ...

core  

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Preclinical Safety Assessment of Antineoplastic Agents Based on Live Non-Pathogenic Enteroviruses

open access: yesБезопасность и риск фармакотерапии
INTRODUCTION. Developing novel medicines based on non-pathogenic enterovirus strains exhibiting oncotropic and oncolytic properties represents an up-to-date and safe approach to complex cancer treatment and postoperative metastasis prevention.
K. V. Sivak   +19 more
doaj   +1 more source

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