Results 81 to 90 of about 1,521,389 (308)

Designing a Multi-Level Governance Model in Complex Organizations Based on Grounded Theory and Meta-Synthesis [PDF]

open access: yesحکمرانی و توسعه
Objective: Multilevel governance is essential for achieving the vision and goals of today’s complex organizations. Therefore, the aim of this research is to present a multilevel governance model for complex organizations using a meta-synthesis of ...
Bahman Ebrahimian   +4 more
doaj   +1 more source

Information Provision for Strategic Planning in Bulgarian SMEs [PDF]

open access: yes
The information provision of strategic planning in small and medium sized enterprises (SMEs) is a subject that provokes the research interest due to the increased importance of strategic planning for the corporate development. This article - based on the
Emil PAPAZOV, Lyudmila MIHAYLOVA
core  

Strategic Planning [PDF]

open access: yesAAOHN Journal, 1989
H L, Brown, K C, Brown
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Strategic Planning, Hypercompetition, and Knowledge Management [PDF]

open access: yes, 2003
When both product andresource markets are turbulentand disruptive, competitiveadvantage has to be continuallyrenewed. But a firm can do this onlyby managing its knowledge.
Akhter, Syed H.
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Identifying and modeling the dimensions of the university's relationship with the external environment from the perspective of ecosystem thinking with the grounded theory method and ISM [PDF]

open access: yesسیاست نامه علم و فناوری
The lack of correct relationship between the university and the external environment (including society, industry, government, etc.) has been and is one of the current social issues of universities.
Mohammad Shamsoddini   +3 more
doaj  

Effect of primer binding sites mutations on the efficacy of measles virus RNA detection using PCR and LAMP techniques

open access: yesБиопрепараты: Профилактика, диагностика, лечение
INTRODUCTION. The high variability of the measles virus RNA genome poses risks of mutations accumulating at primer binding sites (complementary binding site), potentially impacting the reliability of molecular measles diagnostics.
G. M. Tsyganova   +4 more
doaj   +1 more source

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