Results 171 to 180 of about 1,042,917 (337)

Toward a new sustainable urban planning

Italian Journal of Planning Practice, 2014
It is clear, as recently established scientifically, that global change is produced byman­made activities carried out on the planet. For a long time, experts have found anomalies and irrationally risky human actions as regards processes which are ...
Romano Fistola
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

BOX 3 - THE ANALYSIS OF HISTORICAL BUILDINGS A brief survey on technical regulations and their effects on urban planning

Italian Journal of Planning Practice, 2014
BOX 3 - THE ANALYSIS OF HISTORICAL BUILDINGS. A brief survey on technical regulations and their effects on urban planning.
Marghetita Giuffrè
doaj  

The state of strategic plans for the health workforce in Africa. [PDF]

BMJ Glob Health, 2019
Afriyie DO, Nyoni J, Ahmat A.
europepmc   +1 more source

Multilingualism and strategic planning for HIV/AIDS-related health care and communication

, 2019
Kathryn Batchelor, Lalbila Aristide Yoda, Féridjou Emilie Georgette Sanon Ouattara, Olivia Hellewell   +3 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

African digital health strategic plans analysis: key weaknesses in contextualization, intervention focus, and technological foresight. [PDF]

NPJ Digit Med
Sylla B, Somda AP, Nikiema JN, Savadogo LGB, Diallo G, Meda N.   +5 more
europepmc   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Mixed-method analysis of published national one health strategic plans. [PDF]

iScience
Wilhelm CS, Desvars-Larrive A, Walzer C.
europepmc   +1 more source