Results 91 to 100 of about 988,232 (246)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Quando a Estratégia como Prática Encontra com a Política Pública de Turismo: o contexto de um sindicato e de empresas associadas do turismo gastronômico no Espírito Santo

Teoria e Prática em Administração, 2015
The goal of this paper is to comprehend the “strategizing” related to tourism policy in the state of Espírito Santo, on a syndicate and enterprises of gastronomic tourism of this state.
Faria, Arilton Marques, Silva, Alfredo Rodrigues Leite da   +1 more
doaj  

Translingual practice as a discursive strategy to shape lifestyle and cultural identity

Humanities & Social Sciences Communications
The paper presents a comprehensive examination of the influence of online translingual practice on the lifestyle choices and identity construction of Chinese youth.
Yunhong Wang, Boyang Peng, Xiaoli Tang
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Strategic entrepreneurship: observations from the practices of cachaça certification / O empreender estratégico: reflexões a partir de práticas de certificação de cachaça

RAM. Revista de Administração Mackenzie, 2018
Purpose: This work seeks to achieve two central goals: 1. identifying entrepreneurial praxis and understanding how they promote the involvement of different individuals in the certification of alembic cachaça and; 2.
André L. Paiva, Daniela M. Andrade, Luiz M. Antonialli, Mozar J. Brito   +3 more
doaj  

Conservation in Saudi Arabia; moving from strategy to practice. [PDF]

Saudi J Biol Sci, 2018
Barichievy C, Sheldon R, Wacher T, Llewellyn O, Al-Mutairy M, Alagaili A.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

STRATEGY AS PRACTICE: A DISCUSSION OF THE EPISTEMOLOGICAL APPROPRIATION OF HISTORICAL-CULTURAL ACTIVITY THEORY BY THE ACTIVITY-BASED VIEW

Faces: Revista de Administração, 2012
As an approach in development, Strategy as Practice appropriates other theories with ontological and epistemological assumptions that converge for the construction of their analytical body.
Marcio Luiz Marietto, Cida Sanches, Manuel Meireles   +2 more
doaj  

European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) Policy Document Development Strategy - Clinical Practice Guidelines, Position Statements and Technological Reviews. [PDF]

Ultrasound Int Open, 2019
Jenssen C, Gilja OH, Serra AL, Piscaglia F, Dietrich CF, Rudd L, Sidhu PS.   +6 more
europepmc   +1 more source