Results 101 to 110 of about 910,791 (289)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Wash Corporate Heads! Business Practice can be Changed via the Dispositions of Executives: Re-socialization towards Implicit Eco-sustainability [PDF]

The present paper is the synopsis of my doctoral dissertation, which assumes that – in addition to rational factors – the dispositions of management also decisively affect business decisions, and thus business executives' mindset and behavioral patterns (
Hrotko, Timur
core   +1 more source

Energizing middle managers' practice in organizational learning [PDF]

, 2018
Purpose This paper aims to consider middle managers' influence on organizational learning by exploring how they cope with demands and tensions in their role and whether their practice affects available team energy.
McKenzie, Jane, Varney, Sharon
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Practicing Capitals Across Fields: Extending Bourdieu to Study Inter-Field Dynamics [PDF]

, 2019
This essay extends a Bourdieusian perspective on the microfoundations of institutions. Drawing on this perspective, we argue that the recursive dynamics of institutions and action orient actors towards the maintenance of distinct and contradictory ...
Anesa, M., Chalkias, K., Jarzabkowski, P., Spee, A. P.   +3 more
core   +2 more sources

Contornando o Estigma: uma análise dos estúdios de tatuagens em Belo Horizonte

Teoria e Prática em Administração, 2014
Small businesses are vital to the economy, contributing to PIB and to job creation. Howerver, most part of these businesses have difficult to survive, what reveals problems in theirs managament processes.
Silva, Alexsandra Nascimento da, Saraiva, Luiz Alex Silva   +1 more
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Strategy in sub-saharan Africa: defining a research agenda for Mauritius [PDF]

, 2008
Do African firms differ in their approach to strategy making? Are they any different to firms from other emerging or developed economies? Despite the proliferations of strategy and international business textbooks over the last decade, there has been ...
Boojihawon, Dev
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source