Results 101 to 110 of about 17,506,218 (372)
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
Nature Physics, 2020 The impending update to the European Strategy for Particle Physics is an apt moment to chart the future of the field - a future that should be supported and ensured.
openaire +2 more sources
, 2007 During the past three months, the focus of the university’s efforts has included the following highlights: Three projects have been identified to meet SNAP strategic messaging needs: an anti-litter exhibit; a volunteer restoration program with ...
Environmental Education Strategy for Nevada
core
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Identifying one university’s prevailing online course accessibility issues
Educational Technology & SocietyOnline and digital learning is becoming more widespread in a post-pandemic world. The rapid expansion of online education has introduced many accessibility concerns that may go unnoticed by inexperienced observers.
Madasen Briggs +4 more
doaj +1 more source
, 2004 In the first three months of this agreement, UNLV has met with the Outside Las Vegas Environmental Education Committee to establish the duties of and create detailed job announcements for the project managers for the Environmental Education Strategy and ...
Environmental Education Strategy for Nevada
core
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source