Results 21 to 30 of about 4,841,074 (245)

Depression, anxiety and suicidal behaviour among college students: Comparisons pre-COVID-19 and during the pandemic

Psychiatry Research Communications, 2021
Background: Many students struggle with psychological problems during their college years. These problems may be even more apparent during the COVID-19 pandemic with the accompanying restrictions and transition to an online learning environment, but few ...
Margaret McLafferty, Natasha Brown, Rachel McHugh, Caoimhe Ward, Ailis Stevenson, Louise McBride, John Brady, Anthony J. Bjourson, Siobhan M. O'Neill, Colum P. Walsh, Elaine K. Murray   +10 more
doaj   +1 more source

Detection of familial hypercholesterolaemia: external validation of the FAMCAT clinical case-finding algorithm to identify patients in primary care

The Lancet Public Health, 2019
Summary: Background: The vast majority of individuals with familial hypercholesterolaemia in the general population remain unidentified worldwide. Recognising patients most likely to have the condition, to enable targeted specialist assessment and ...
Stephen Weng, PhD, Joe Kai, ProfMD, Ralph Akyea, MPH, Nadeem Qureshi, ProfDM   +3 more
doaj   +1 more source

Obesity, metabolic health and clinical outcomes after incident cardiovascular disease: A nationwide population‐based cohort study

Journal of Cachexia, Sarcopenia and Muscle, 2023
Background The association between metabolic syndrome and increased cardiovascular disease (CVD) risk is well‐established. However, in patients with incident CVD, the relationship between obesity, metabolic health, and subsequent CVD and mortality ...
Ralph K. Akyea, George Ntaios, Wolfram Doehner   +2 more
doaj   +1 more source

Stratified versus usual care for the management of primary care patients with sciatica: the SCOPiC RCT

Health Technology Assessment, 2020
Background: Sciatica has a substantial impact on patients and society. Current care is ‘stepped’, comprising an initial period of simple measures of advice and analgesia, for most patients, commonly followed by physiotherapy, and then by more intensive ...
Nadine E Foster, Kika Konstantinou, Martyn Lewis, Reuben Ogollah, Benjamin Saunders, Jesse Kigozi, Sue Jowett, Bernadette Bartlam, Majid Artus, Jonathan C Hill, Gemma Hughes, Christian D Mallen, Elaine M Hay, Danielle A van der Windt, Michelle Robinson, Kate M Dunn   +15 more
doaj   +1 more source

Thermocline management of stratified tanks for heat storage [PDF]

, 2009
Stratified tanks are useful for maximising the thermal energy efficiency of non-continuous and semi-continuous processes. Liquid at two or more dissimilar temperatures is stored within the same tank to provide a buffer for variations in heating and ...
Walmsley, Michael R.W., Riley, Joseph, Atkins, Martin John   +2 more
core   +1 more source

Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models

BMJ Open, 2020
Introduction Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. With advances in early diagnosis and treatment of CVD and increasing life expectancy, more people are surviving initial CVD events.
Joe Kai, Nadeem Qureshi, Stephen F Weng, Folkert W Asselbergs, Anthony S Wierzbicki, Riyaz S Patel, Ralph K Akyea, Jo Leonardi-Bee, Paul Durrington, Oluwaseun H Ibiwoye   +9 more
doaj   +1 more source

Educational needs in diagnosing rare diseases: A multinational, multispecialty clinician survey

Genetics in Medicine Open, 2023
Purpose: Recognizing rare diseases (RDs) and initiating appropriate investigation and referral is critical for timely diagnosis. Unfortunately, patients with RDs experience significant diagnostic delays, potentially leading to inappropriate or harmful ...
S. Christy Rohani-Montez, Jennifer Bomberger, Cong Zhang, Jacob Cohen, Lucy McKay, William R.H. Evans   +5 more
doaj   +1 more source

Measuring upper limb function in MS: Which existing patient reported outcomes are fit for purpose?

eNeurologicalSci, 2020
Background: Multiple Sclerosis (MS) clinical trials increasingly focus on progressive and advanced MS, with upper limb function (ULF) as a key outcome.
James Close, Kathryn Baines, Laurie Burke, Jeremy Hobart   +3 more
doaj   +1 more source

Multi-dimensional relationships among dementia, depression and prescribed drugs in England and Wales hospitals

BMC Medical Informatics and Decision Making, 2022
Background  Dementia is a group of symptoms that largely affects older people. The majority of patients face behavioural and psychological symptoms (BPSD) during the course of their illness. Alzheimer’s disease (AD) and vascular dementia (VaD) are two of
Alok Joshi, Stephen Todd, David P. Finn, Paula L. McClean, KongFatt Wong-Lin   +4 more
doaj   +1 more source

Age and Age-Related Diseases: Role of Inflammation Triggers and Cytokines

Frontiers in Immunology, 2018
Cytokine dysregulation is believed to play a key role in the remodeling of the immune system at older age, with evidence pointing to an inability to fine-control systemic inflammation, which seems to be a marker of unsuccessful aging.
Irene Maeve Rea, Irene Maeve Rea, Irene Maeve Rea, David S. Gibson, Victoria McGilligan, Susan E. McNerlan, H. Denis Alexander, Owen A. Ross, Owen A. Ross, Owen A. Ross   +9 more
doaj   +1 more source