Results 31 to 40 of about 30,159 (217)
Current Oncology, 2021 Risk-stratified pathways of survivorship care seek to optimize coordination between cancer specialists and primary care physicians based on the whole person needs of the individual.
Dominique Tremblay +5 more
doaj +1 more source
Programme Grants for Applied Research, 2023 Background Usual primary care for patients with musculoskeletal pain varies widely and treatment outcomes are suboptimal. Stratified care involves targeting treatments according to patient subgroups, in the hope of maximising treatment benefit and ...
Foster Nadine E +15 more
doaj +1 more source
BMJ Open, 2022 Background Stratified care has the potential to be efficient in addressing the physical and psychosocial components of low back pain (LBP) and optimise treatment outcomes essential in low-income countries.
Kay Stevenson +4 more
doaj +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Energy Conservation and Second-Order Statistics in Stably Stratified Turbulent Boundary Layers [PDF]
Environmental Fluid Mechanics (2009), 2006 We address the dynamical and statistical description of stably stratified turbulent boundary layers with the important example of the atmospheric boundary layer with a stable temperature stratification in mind. Traditional approaches to this problem, based on the profiles of mean quantities, velocity second-order correlations, and dimensional estimates
arxiv +1 more source
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Machine Learning Approaches for Type 2 Diabetes Prediction and Care Management [PDF]
arXiv, 2021 Prediction of diabetes and its various complications has been studied in a number of settings, but a comprehensive overview of problem setting for diabetes prediction and care management has not been addressed in the literature. In this document we seek to remedy this omission in literature with an encompassing overview of diabetes complication ...
arxiv
Turbulent Fluxes in Stably Stratified Boundary Layers [PDF]
Physica Scripta T132, 014010 (2008), 2008 We present an extended version of an invited talk given on the International Conference "Turbulent Mixing and Beyond". The dynamical and statistical description of stably stratified turbulent boundary layers with the important example of the stable atmospheric boundary layer in mind is addressed.
arxiv +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source