Results 81 to 90 of about 392,560 (289)
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Dual Transformation of Auxiliary Variables by Using Outliers in Stratified Random Sampling
MathematicsTo estimate the finite population variance of the study variable, this paper proposes an improved class of efficient estimators using different transformations. When both the minimum and maximum values of the auxiliary variable are known and the ranks of
Mohammed Ahmed Alomair, Umer Daraz
doaj +1 more source
Toward a principled sampling theory for quasi-orders
Frontiers in Psychology, 2016 Quasi-orders, that is, reflexive and transitive binary relations, have numerous applications. In educational theories, the dependencies of mastery among the problems of a test can be modeled by quasi-orders.
Ali Ünlü, Martin Schrepp
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Stochastic comparisons of stratified sampling techniques for some Monte Carlo estimators
, 2011 We compare estimators of the (essential) supremum and the integral of a function $f$ defined on a measurable space when $f$ may be observed at a sample of points in its domain, possibly with error.
Goldstein, Larry +2 more
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Iranian Journal of Public Health, 2014 Traditional survey methods may cause refusals to respond or untruthful replies when encounter the sensitive questions. The Randomized Response Technique (RRT) is designed to decrease social desirability bias and obtain reliable estimates.
Xiangyu Chen +5 more
doaj
A methodology for small scale rural land use mapping in semi-arid developing countries using orbital imagery. Part 5: Experimental and operational techniques of mapping land use [PDF]
The author has identified the following significant results. Scope of the preprocessing techniques was restricted to standard material from the EROS Data Center accompanied by some enlarging procedures and the use of the diazo process.
Lock, B. F., Vangenderen, J. L.
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WILCOXON ESTIMATOR BASED ON STRATIFIED RANDOM SAMPLE
Memoirs of the Faculty of Science, Kyushu University. Series A, Mathematics, 1974 Let population with continuous and symmetric c.d.f. F(X-θ) be classified into preassigned number L of strata. Let Zi1, Zi2,...,Zini. be ni independent observations from the i-th stratum (i=1∼L).
openaire +2 more sources