Results 101 to 110 of about 8,104,821 (348)

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Digital collaborative exploration and practice of ground vibration test for full-scale aircraft

open access: yesHangkong gongcheng jinzhan
The ground vibration test of full-scale aircraft has the characteristics of multiple coordination units, complex system, long implementation time and high risk.
BAI Chunyu, LIANG Sen, SONG Qiaozhi
doaj   +1 more source

Structural Strength of Laminated Glass

open access: yesChallenging Glass Conference Proceedings, 2018
The subject area "structural strength of materials" is defined generally as а complex of strength characteristics of materials and structural elements, obtained under special mechanical tests.
Yurii Rodichev   +4 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Prediction of Random Crack Propagation Life of Thin Porous Plate with Multiple Site Damage

open access: yesEngineering Proceedings
Based on the crack propagation rate test of LY12CZ aluminum alloy flat plate, the distribution characteristics of Paris formula parameters were characterized by the three-parameter logarithmic normal distribution, and a LY12CZ random crack propagation ...
Hanbin Sun, Xianmin Chen, Jun Yang
doaj   +1 more source

Solidification of APC residues using PFA

open access: yes, 2009
A pulverised fuel ash (pfa) classed as a waste due to high loss on ignition (LoI) was blended with waste alkali and used to solidify air pollution control (APC) residue from a waste incinerator.
Black, L, Shirley, R
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

open access: yesFEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh   +7 more
wiley   +1 more source

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