Results 71 to 80 of about 5,501,103 (350)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Structural strength analysis of a rotary drum mower during harvesting

Journal of Agricultural Engineering
A Rotary Drum Mower (RDM) is a tractor-mounted mechanism used for harvesting green fodder crops. It faces dynamic forces from rough field surfaces and cutting resistance, posing design challenges and potential failures. This study aims to present a well-
Kursat H. Celik, Ibrahim Akinci, Nuri Caglayan, Allan E.W. Rennie   +3 more
doaj   +1 more source

Prediction of concrete strength using ultrasonic pulse velocity and artificial neural networks [PDF]

, 2009
Ultrasonic pulse velocity technique is one of the most popular non-destructive techniques used in the assessment of concrete properties. However, it is very difficult to accurately evaluate the concrete compressive strength with this method since the ...
Ali, Berriman, del Rio, Franci Kavčič, Goran Turk, Gregor Trtnik, Hola, Hola, Hong-Guang, Kewalramani, Kheder, Lee, Mehta, Ohdaira, Popovics   +14 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Strength analysis and structural optimization of UAV airframe

Frontiers in Mechanical Engineering
IntroductionWith the booming low-altitude economy, UAVs drive transformative changes across sectors, but their design must balance lightweight demands and structural integrity.
Longhai Ye, Yanpeng Zhao, Haifeng Zhang, Yao Zhang, Jiming Lv, Zonghan Yang   +5 more
doaj   +1 more source

The concept of modification and analysis of the strength of steel roadway supports for coal mines in the Soma Basin in Turkey

Studia Geotechnica et Mechanica, 2018
The article presents a comparison of the roadway supports currently used in mines in the Soma basin in Turkey with new one proposed by Huta Łabędy and Central Mining Institute (GIG) in terms of resistance parameters and work in conditions of specific ...
Grodzicki Marek, Rotkegel Marek
doaj   +1 more source

Strength analysis of slewing bearings

Transportation Research Procedia, 2019
Abstract The thesis deals with the creation of a 3D model of the slewing bearing and its functional parts on which the axial load acts. In order to investigate the load applied to the bearing as a whole and to examine the effect of forces on the rolling body and the rolling tracks, it was necessary to create a computational 3D model with ...
Rudolf Skyba, Slavomír Hrček, Lukáš Smetánka, Maroš Majchrák   +3 more
openaire   +1 more source

Torsional strength analysis of universal joint’s ZP-11A due to yokes modification and materials [PDF]

, 2022
Hartono Yudo, Andi Setiawan, Ocid Mursid, Muhammad Iqbal   +3 more
openalex   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source