Results 71 to 80 of about 26,250,209 (255)

Aerodynamic design and strength check of a two-stage dual-rotor opposed centrifugal compressor

Zhongguo Jianchuan Yanjiu, 2019
[Objectives] To accomplish the design of a two-stage dual-rotor opposed centrifugal compressor for a small gas turbine,[Methods] the compressor is subject to aerodynamic design and three-dimensional flow field check by using the software Concepts NREC ...
Geng Shaojuan, Ni Ming, Ding Linchao, Wang Wentao, Zhang Xiaoyu   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Upper Body Muscle Strength and Endurance in Relation to Peak Exercise Capacity During Cycling in Healthy Sedentary Male Subjects.

, 2011
Segerström, AB, Holmbäck, AM, Elzyri, T, Eriksson, KF, Ringsberg, K, Groop, L, Thorsson, O, and Wollmer, P. Upper body muscle strength and endurance in relation to peak exercise capacity during cycling in healthy sedentary male subjects.
Per Wollmer, Leif Groop, Karin Ringsberg, Groop, Leif, Thorsson, Ola, Tornberg, Åsa, Ringsberg, Karin, Ola Thorsson, Karl-Fredrik Eriksson, Anna M Holmbäck, Elzyri, Targ, Eriksson, Karl-Fredrik, Wollmer, Per, Targ Elzyri, Drake, Anna Maria, Åsa B Segerström, Groop, Leif,, Tornberg, Åsa,, Elzyri, Targ,, Ringsberg, Karin,, Wollmer, Per,, Eriksson, Karl-Fredrik,, Drake, Anna Maria,, Thorsson, Ola,, Lund University.   +24 more
core   +1 more source

Structural strength analysis of a rotary drum mower during harvesting

Journal of Agricultural Engineering
A Rotary Drum Mower (RDM) is a tractor-mounted mechanism used for harvesting green fodder crops. It faces dynamic forces from rough field surfaces and cutting resistance, posing design challenges and potential failures. This study aims to present a well-
Kursat H. Celik, Ibrahim Akinci, Nuri Caglayan, Allan E.W. Rennie   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Prediction ability analysis of phenomenological strength criteria for composites [PDF]

The article examines and assesses the phenomenological strength theory of composite materials. A comparative analysis of the theoretical envelopes was conducted for each criterion.
Huang, T., Huang T.
core   +1 more source

MODELLING AND ANALYSIS OF THE MOBILE PLATFORM UNDER ITS WORK CONDITIONS [PDF]

Scientific Journal of Silesian University of Technology. Series Transport, 2014
In this work the calculation model of mobile platform, type HAULOTTE - H1150E, and its strength analysis under work conditions have been completed. The model has been obtained by using finite element method with application of the SolidWorks package. The
Rafał GOSZYC, Bogdan POSIADAŁA, Paweł WARYŚ   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Mathematical Modeling of the Load of an Open Wagon Body with Corrugated Sheet Metal

Mathematics
This article presents mathematical modeling results in terms of the load-bearing properties of an open wagon body with corrugated sheet metal. The main hypothesis of this study is that the use of corrugated sheet metal will improve wall cladding strength
Juraj Gerlici, Alyona Lovska, Mykhailo Pavliuchenkov, Ján Dižo, Pavol Šťastniak   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source