Results 71 to 80 of about 1,520,494 (296)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Means of Speed-Strength Abilities Development in Physical Training Classes with 10th Graders

Physical Education Theory and Methodology, 2016
The purpose of the research is to determine the means of development of speed-strength abilities manifesting in jump-offs in jumping exercises in classes with the 10th graders in order to improve the compliance with the standards of physical preparedness.
С. А. Пашкевич, Я. В. Матвієнко   +1 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Operational Reliability of Steel Ropes in Terms of Mechanical Properties of Wires Using Control Charts

Applied Sciences
The objective of this paper is to evaluate the capability of various steel rope manufacturers to maintain the desired variability within the strength class of wires used in the production of steel ropes.
Marcela Malindzakova, Pavel Peterka
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Development of speed and strength abilities of students in mini-football sectional classes

Вестник Северо-Кавказского федерального университета
Introduction. Modern educational paradigm involves a sociocultural environment creation where there is a citizen’s formation as a subject of spiritual and intellectual self-development with ideology, values, and norms for the reality transformation.
N. L. Nizhneva-Ksenofontova, N. N. Nizhneva, A. G. Mikhaylova   +2 more
doaj   +3 more sources

Vortices in a rotating BEC under extreme elongation

, 2005
We investigate a non-axisymmetric rotating BEC in a limit of rotation frequency for which the BEC transforms into a quasi-one-dimensional system. We compute the vortex lattice wavefunction by minimizing the Gross-Pitaevskii energy functional in the ...
A. A. Abrikosov, J. J. Palacios, L. Landau, L. P. Pitaevskii, M. Tinkham, P. Sánchez-Lotero, T. Chakraborty   +6 more
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Study of brazilian structural concrete block conformity

Revista IBRACON de Estruturas e Materiais, 2018
This paper presents a study of the conformity of structural concrete blocks manufactured and used in masonry construction in Brazil. It is based on compressive strength tests, on dimensional analysis and absorption tests of over six thousand samples from
W. C. SANTIAGO, A. T. BECK
doaj   +2 more sources

Strength development in adolescents in physical education classes

International Physical Medicine & Rehabilitation Journal, 2019
Objective:The objective of this study was to gain muscle strength in all its variables in adolescents after a strength training program in physical education classes for a period of 12 weeks - a strength training program in physical education classes at a State School of Ponta Pora (Brazil) was applied.
Raphael Oliveira Ramos Franco Netto, Paulo Ricardo Cardoso Klidzio, Adriana Langer   +2 more
openaire   +1 more source