Results 91 to 100 of about 2,078,028 (291)
, 2016 Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally non-volatile long-term plasticity changes have been implemented in nanoelectronic synapses for neuromorphic applications, recent
Roy, Kaushik, Sengupta, Abhronil
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Space and Culture, India, 2022 COVID-19 and the lockdown are not the worst things to have been imposed upon the people with whom I work. In fact, their lives marinated in childhood sexual trauma, abuse, neglect, family violence, severe mental ill health, and/or disability, have ...
Anne Riggs
doaj
Strengthening entrepreneurship through coaching and developing competencies [PDF]
, 2011 Strengthening entrepreneurship is an important strategy for stimulating the transition to sustainable agriculture. But how is that done? One example is the Interactive Strategic Management method, which supports entrepreneurs in the creation and ...
Beldman, A.C.G.
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Wacana Constitutional Questions dalam Situs Mahkamah: Konteks e-Deliberative Democracy
Jurnal Konstitusi, 2016 Pengantar Pertengahan akhir tahun 2010 ini terdapati perkara yang menyita perhatian publik ditingkat nasional seperti putusan dalam perkara permohonan Pengujian Undang-Undang Nomor 16 Tahun 2004 tentang Kejaksaan Republik Indonesia terhadap Undang ...
Anom Surya Putra
doaj +1 more source
Croatia: introducing and strengthening the non-university sector [PDF]
, 2016 The report concerns Croatia's policy to strengthen its non-university higher education provision and increase horizontal differentiation among its higher education institutions and study programmes.
Brankovic, Jelena, Vukasovic, Martina
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RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Participatory Deliberative Democracy for Peace in El Salvador
Journal of Deliberative Democracy, 2019 Postconflict societies such as El Salvador, surpassing 25 years of relative peace since signing the 1992 Chapultepec Peace Accords, have employed many mechanisms to rebuild and establish lasting peace.
Marcia Mundt
doaj +2 more sources
FEBS Open Bio, EarlyView.Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani +7 more
wiley +1 more source