Antimicrobial-resistant Streptococcus pneumoniae
Canadian Journal of Infectious Diseases, 1999 M Lovgren, JA Talbot
doaj +1 more source
Rare Occurrence of Prosthetic Knee Septic Arthritis Due to Streptococcus viridans in the Background of a Dental Procedure [PDF]
, 2019 Tikal Kansara +3 more
openalex +1 more source
Advanced Science, EarlyView.The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi +15 more
wiley +1 more source
Advanced Science, EarlyView.Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin +14 more
wiley +1 more source
Molecular analysis of representative Streptococcus gordonii Spp phase variants reveals no differences in the glucosyltransferase structural gene, gtfG [PDF]
, 1997 M. Margaret Vickerman +2 more
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Discovery of a Potent and Selective TEAD Degrader with Durable Degradation Activity
Advanced Science, EarlyView.KG‐FP‐003, a highly potent TEAD‐YAP PROTAC derived from the patented inhibitor is developed. It selectively degrades endogenous TEAD proteins in HiBiT systems without IMiD‐related off‐target effects. Screening across 867 cancer cell lines revealed broad and superior anti‐tumor activity, highlighting its therapeutic potential through targeted TEAD ...
Linhui Cao +25 more
wiley +1 more source
Frequency of Antibiotic Resistance and Virulence Factors in <i>Streptococcus agalactiae</i> Isolated from Vaginal and Urine Samples of Pregnant Women in Yazd, Iran: A Cross-sectional Study [PDF]
Nastaran Azartoos +2 more
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Streptococcus pyogenes type M12 protein shows selective binding to some human immunoglobulin G3 myeloma proteins [PDF]
, 1994 Peter Johansson +4 more
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A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules
Advanced Science, EarlyView.Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang +6 more
wiley +1 more source