Results 111 to 120 of about 407,256 (265)
The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset
Advanced Science, EarlyView.The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng +22 more
wiley +1 more source
Organoid Modeling of Mouse Anterior Tongue Epithelium Reveals Regional and Cellular Identities
Advanced Science, EarlyView.The tongue's anterior epithelium is maintained by region‐specific stem/progenitor cells, yet in vitro models are limited. Long‐term expanding organoids are developed from adult mouse anterior tongue that retain region‐specific identity, cellular diversity, and gene regulatory features. These organoids differentiate into keratinocytes, Merkel‐like cells,
Seok‐Young Kim +12 more
wiley +1 more source
Advanced Science, EarlyView.Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park +19 more
wiley +1 more source
Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E
Advanced Science, EarlyView.Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple models, secondary necrosis occurred regardless of gasdermin E presence, challenging prior claims and redefining the understanding of how apoptotic cells ...
Shubhangi Gavali +9 more
wiley +1 more source
Strong mitogenic effect for murine B lymphocytes of an immunosuppressor substance released by Streptococcus intermedius [PDF]
, 1986 Mário Arala‐Chaves +3 more
openalex +1 more source
Peptide Electrostatic Modulation Directs Human Neural Cell Fate
Advanced Science, EarlyView.This study explores the effect of charge on the bioactivity of peptide‐based supramolecular materials. The design of a peptide library with varying charges that self‐assemble into supramolecular fibers is presented, demonstrating how the surface charge of these fibers, used as artificial extracellular matrices, influences the fate of human neural ...
Laura Perez‐Chirinos +10 more
wiley +1 more source
Lack of correlation between in vitro and in vivo studies of combinations of rifampin plus vancomycin or beta-lactam antibiotics against Streptococcus pneumoniae [PDF]
, 1996 F Tuban +2 more
openalex +1 more source