Results 61 to 70 of about 88,036 (280)
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
, 2015 Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X +6 more
core +2 more sources
Advanced Science, EarlyView.Base editing enables precise nucleotide substitutions but limited by bystander editing. This study engineers plant base editors by fusing optimized TadA variants with PAM‐flexible SpRY nickase, enabling A‐to‐G, C‐to‐T, and dual‐base conversions in a highly condensed window (≤3 nucleotides). Additionally, TadDBE (TadA Dual‐Base Editor)‐mediated directed
Kangli Sun +14 more
wiley +1 more source
The Shift of Bacterial Sensitivity with Antibiotics in Acute Tonsillitis
Journal of Nobel Medical College, 2021 Background: The infection of tonsil may occur primarily or secondarily as a result of upper respiratory tract infection, usually preceded by a viral infection. Bacterial tonsillitis is most commonly caused by Streptococcus pyogenes.
Brihaspati Sigdel
doaj +1 more source
Coinfection of Leishmania (Viannia) braziliensis and Streptococcus pneumoniae in multiple cutaneous lesions [PDF]
, 2016 Key learning points Cutaneous leishmaniasis is the most common clinical disease caused by all the Leishmania species that are pathogenic to humans. Other bacterial coinfections of Leishmania lesions have been described, but this is the first report of ...
Chiapello, Laura Silvina +6 more
core +2 more sources
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes. [PDF]
, 2020 Anti-CRISPRs (Acrs) are small proteins that inhibit the RNA-guided DNA targeting activity of CRISPR-Cas enzymes. Encoded by bacteriophage and phage-derived bacterial genes, Acrs prevent CRISPR-mediated inhibition of phage infection and can also block ...
Doudna, Jennifer A +5 more
core +3 more sources
Advanced Science, EarlyView.A next‐generation cytosine base editor (zTadCBE) and other variants are developed by combining the high‐efficiency (TadCBEa) and low‐indel (TadCBEMax) architectures, followed by the introduction of zebrafish‐optimized mutations (V82S, Q154R) in the TadA domain.
Wei Qin +7 more
wiley +1 more source
A Streptococcus Quorum Sensing System Enables Suppression of Innate Immunity
mBio, 2021 Streptococcus ...
Kate M. Rahbari +2 more
doaj +1 more source
Protective vaccination in the horse against _Streptococcus equi_ with recombinant antigens [PDF]
, 2009 _Streptococcus equi_ subspecies _equi_ (_S. equi_) is a clonal, equine host-adapted pathogen of global importance that causes a highly contagious suppurative lymphodendopathy of the head and neck, more commonly known as Strangles.
Andrew Waller +6 more
core +1 more source
The Influence of Bacteriophage on Streptococcus pyogenes [PDF]
Journal of General Microbiology, 1955 By the selective action of certain bacteriophages on cultures of susceptible streptococci it is possible to alter or enhance certain of their characteristics. The extractable M antigen may be greatly increased; non-mucoid strains may become completely mucoid with or without the increase in M antigen.
openaire +3 more sources
Penicillin-resistant Streptococcus pyogenes? [PDF]
FEMS Microbiology Letters, 2011 Dear Editor, We read with interest the article ‘Epidemiological characterization of Streptococcus pyogenes isolated from patients with multiple onsets of pharyngitis’ by Ogawa et al . (2011). The authors address the important issue of recurrent …
Magnus Rasmussen, Fredrik Kahn
openaire +3 more sources