Results 121 to 130 of about 343,019 (395)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Streptococcus suis Serotype 2 Capsule In Vivo

open access: yesEmerging Infectious Diseases, 2016
Many Streptococcus suis isolates from porcine endocarditis in slaughterhouses have lost their capsule and are considered avirulent. However, we retrieved capsule- and virulence-recovered S. suis after in vivo passages of a nonencapsulated strain in mice,
Jean-Philippe Auger   +6 more
doaj   +1 more source

Streptococcus suis in humans, Thailand.

open access: yesEmerging infectious diseases, 2008
Streptococcus suis in Humans ...
Daisuke Takamatsu   +9 more
openaire   +3 more sources

Porcine Streptococcus Suis in Minnesota [PDF]

open access: yesJournal of Veterinary Diagnostic Investigation, 1992
the number of new water acres used for catfish production in the delta region of west-central Mississippi. This increase in production was reflected by the establishment of the fish health diagnostic laboratory at Belzoni in June 1986 and the subsequent increase in the aquatic diagnostic case load of the Mississippi Cooperative Extension Service.
L, Galina, J E, Collins, C, Pijoan
openaire   +2 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Case of Streptococcus suis meningitis in a French cooker and review [PDF]

open access: yesJournal of Microbiology and Infectious Diseases, 2016
Streptococcus suis is an emerging zoonotic pathogen, increasingly reported worldwide and especially in Asia. S. suis remains rare in France but is responsible for outbreaks in Asia, causing meningitis, septicemia, endocarditis, arthritis and septic ...
Astrid Malézieux-Picard, Anne De monte, Nicolas Degand
doaj   +1 more source

Toll-Like Receptor 2-Independent Host Innate Immune Response against an Epidemic Strain of Streptococcus suis That Causes a Toxic Shock-Like Syndrome in Humans [PDF]

open access: yes, 2013
Streptococcus suis is an emerging zoonotic agent causing meningitis and septicemia. Outbreaks in humans in China with atypical cases of streptococcal toxic shock-like syndrome have been described to be caused by a clonal epidemic S.
Gottschalk, Marcelo   +4 more
core   +2 more sources

Streptococcus suis: An Emerging Human Pathogen [PDF]

open access: yesClinical Infectious Diseases, 2009
Streptococcus suis infection is acquired through exposure to contaminated pigs or pig meat. Over the past few years, the number of reported S. suis infections in humans has increased significantly, with most cases originating in Southeast Asia, where there is a high density of pigs.
Wertheim, H   +3 more
openaire   +4 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

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