Results 151 to 160 of about 343,019 (395)

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Application of the Phage Lysin Ply5218 in the Treatment of Streptococcus suis Infection in Piglets

Viruses, 2019
Streptococcus suis (S. suis) is a gram-positive bacterium and zoonotic pathogen. Currently it poses a serious problem in the swine industry due to the emergence of antibiotic-resistant bacteria. Thus, novel antimicrobials against S.
Zhaofei Wang, Jingjiao Ma, Jian Wang, Denghui Yang, Licheng Kong, Qiang Fu, Yuqiang Cheng, Hengan Wang, Yaxian Yan, Jianhe Sun   +9 more
doaj   +1 more source

Aerococcus viridans Phage Lysin AVPL Had Lytic Activity against Streptococcus suis in a Mouse Bacteremia Model [PDF]

, 2023
Hengyu Xi, Yao Fu, Chong Chen, Xin Feng, Wenyu Han, Jingmin Gu, Yalu Ji   +6 more
openalex   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Draft Genome Sequences of Three Porcine Streptococcus suis Isolates Which Differ in Their Susceptibility to Penicillin [PDF]

, 2019
The draft genome sequences of three Streptococcus suis isolates, IMT40343, IMT40201, and IMT40738, are presented here. These isolates were obtained from bronchoalveolar lavage fluid of healthy and diseased weaners from different German piglet-producing ...
Brauns, Jasmin, Eichhorn, Inga, Höltig, Doris, Kadlec, Kristina, Müller, Petra, Nathaus, Rolf, Niemann, Lisa, Schwarz, Stefan, Schäkel, Franziska, Wendt, Michael   +9 more
core   +1 more source

Additional file 3 of Piglet innate immune response to Streptococcus suis colonization is modulated by the virulence of the strain

, 2021
Carlos Neila‐Ibáñez, Louise Brogaard, Lola Pailler‐García, Jorge Martínez, Joaquím Segalés, Mariela Segura, Peter M. H. Heegaard, Virginia Aragón   +7 more
openalex   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

A small RNA from Streptococcus suis epidemic ST7 strain promotes bacterial survival in host blood and brain by enhancing oxidative stress resistance

Virulence
Streptococcus suis is a Gram-positive pathogen causing septicaemia and meningitis in pigs and humans. However, how S. suis maintains a high bacterial load in the blood and brain is poorly understood.
Zijing Liang, Shuoyue Wang, Xinchi Zhu, Jiale Ma, Huochun Yao, Zongfu Wu   +5 more
doaj   +1 more source

Characterization of the zinc metalloprotease of Streptococcus suis serotype 2

Veterinary Research, 2018
Streptococcus suis is a swine pathogen and zoonotic agent responsible for meningitis and septic shock. Although several putative virulence factors have been described, the initial steps of the S. suis pathogenesis remain poorly understood.
Audrey Dumesnil, Jean-Philippe Auger, David Roy, Désirée Vötsch, Maren Willenborg, Peter Valentin-Weigand, Pyong Woo Park, Daniel Grenier, Nahuel Fittipaldi, Josée Harel, Marcelo Gottschalk   +10 more
doaj   +1 more source