Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness
The works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
Jack O' Callaghan +3 more
wiley +1 more source
Biodiversity and Natural Product Potential of Indonesian Actinomycetes. [PDF]
Karissa E +4 more
europepmc +1 more source
Metagenomic Insights Into Microbial Diversity of Tea Rhizosphere of the Kangra Valley
Tea rhizosphere microbial communities in Kangra Valley. ABSTRACT This study provides the first metagenomic assessment of microbial diversity from the tea rhizosphere of the Kangra valley. Tea rhizosphere soil samples were collected from 4 locations (Dharamshala, Baijnath, Palampur, and Joginder Nagar) of the Kangra valley.
Rishu Thakur +3 more
wiley +1 more source
Distribution of lactone-signaling system for expression of secondary metabolite biosynthetic gene clusters in Streptomyces species. [PDF]
Teshima A, Inada K, Arakawa K.
europepmc +1 more source
Production of indigoidine (IND) increased from 1.04 to 2.76 g/L using an optimized LB medium composed of glucose, l‐glutamine, tryptone, yeast extract, MgSO4·7H2O, and KH2PO4. The IND has significant inhibition properties against amylase and lipase enzymes, stimulates AMPK and AKT pathways, and improves glucose uptake.
Tahani Ali Asseri
wiley +1 more source
A qPCR identification scheme to detect the most common causative agents of actinomycetoma in Africa. [PDF]
Watson AK +13 more
europepmc +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Antimicrobial Trioxacarcin 1,2-Dihydroxyanthraquinones from the Bacterium <i>Streptomyces</i> sp. 127Q Isolated from the Stingless Bee <i>Tetragonula carbonaria</i>. [PDF]
Filimonova A, Spiteller D.
europepmc +1 more source
ABSTRACT Respiratory syncytial virus (RSV) infection induces significant structural remodeling of the pulmonary extracellular matrix (ECM). While in vivo models demonstrate increased tissue synthesis of pre‐alpha‐inhibitor (P⍺I) and heavy chain 3 (HC3), which covalently modifies and stabilizes hyaluronan (HA), the primary cellular source of this ...
Sydney J. Clark +8 more
wiley +1 more source
Unravelling the genomic potential of sponge-associated Streptomyces sp. BLC 17-3 from Indonesia for mannooligosaccharide production. [PDF]
Rahmani N +15 more
europepmc +1 more source

