Total Synthesis of Chaxalactin B, a Rare 22‐Membered Macrolactone
The first total synthesis of the antibacterial 22‐membered macrolactone chaxalactin B has been accomplished in 23 steps (longest linear sequence). Key transformations feature a stereoselective Marshall propargylation, a Suzuki–Miyaura coupling for the assembly of the main C1–C9 and C10–C25 fragments, and a late‐stage Shiina macrolactonization ...
Ophélie Montiège +7 more
wiley +1 more source
The Oxytetracycline Producer <i>Streptomyces lydicamycinicus</i> bja295 and Its Genomic Context. [PDF]
Dobryakov MY, Buyuklyan JA, Biryukov MV.
europepmc +1 more source
Using shotgun metagenomic sequencing and untargeted metabolomics, we characterized the microbial communities and metabolic profiles across the stomach, small intestine, and large intestine of Rhabdophis himalayanus. Although overall microbial diversity was similar among digestive tract segments, distinct taxonomic, functional, and metabolic differences
Ji Chen +9 more
wiley +1 more source
From antibiotic to chalkophore: the biology and evolution of SF2768 in Streptomyces. [PDF]
Ueda K.
europepmc +1 more source
Parasite‐Derived IL‐33 Inhibitors Prevent Bleomycin‐Induced Lung Fibrosis
Infection with the intestinal helminth Heligmosomoides polygyrus bakeri, or administration of the parasite products (HES), or administration of recombinant HpARI2+HpBARI_Hom2 can all suppress the development of lung fibrosis in the mouse bleomycin model, via suppression of the IL‐33 pathway. Graphic abstract created in BioRender. McSorley, HJ.
Samuele Di Carmine +11 more
wiley +1 more source
Unlocking the Bioactive Potential of Streptomyces: A Multidisciplinary Approach to Strain Improvement. [PDF]
Goraya A +5 more
europepmc +1 more source
Roasted and non‐roasted Argania spinosa seed oils were evaluated in streptozotocin‐induced diabetic rats. Biochemical and histopathological analyses assessed glucose regulation, lipid metabolism, oxidative stress, liver enzymes, glycogen content, and tissue architecture.
Nour Elhouda Daoudi +9 more
wiley +1 more source
<i>Streptomyces songxianensis</i> sp. nov. SX92<sup>T</sup>: biocontrol of tobacco black shank and modulation of the rhizosphere microbiome. [PDF]
Zhang M +6 more
europepmc +1 more source
From Rhizosphere to Resistance: Microbe‐Plant Interactions in Eco‐Smart Biocontrol
Conceptual framework of eco‐smart biocontrol: Root exudates released by plants shape rhizosphere microbial community assembly by selectively recruiting beneficial microorganisms. These microbes suppress phytopathogens through direct mechanisms such as antibiosis, parasitism, enzyme production, and niche competition, while simultaneously activating ...
Shilpy Singh +5 more
wiley +1 more source
Intra- and inter-biosynthetic gene cluster allelic variation as drivers of chemical diversification in Streptomyces. [PDF]
Nayeb G Hosseini G, Barona-Gómez F.
europepmc +1 more source

