Results 31 to 40 of about 690,437 (335)
Background: Drug-resistant tuberculosis is a major problem worldwide. Based on the knowledge of specific mutations occurring in Mycobacterium tuberculosis genome, drug resistance can be detected earlier.
Imane Chaoui+8 more
doaj +1 more source
Selman Abraham Waksman — a Great Scientist and One of the Greatest Benefactors of Mankind
The article presents in chronological order the main aspects of the discovery of the first antituberculous drug — streptomycin and information about Nobel Prize winner in physiology and medicine of Ukrainian origin — Selman Abraham Waksman.
D.V. Rotar
doaj +1 more source
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp+5 more
wiley +1 more source
Characterization of Streptomycin Resistance in Isolates of Erwinia amylovora in California.
In surveys from 2006 to 2014, streptomycin resistance in Erwinia amylovora from pear-growing areas in California declined from very high incidence in 2006 and 2007 to very low incidence in 2013 and 2014.
H. Förster+3 more
semanticscholar +1 more source
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt+4 more
wiley +1 more source
Anti-microbial drugs are widely employed for the treatment and cure of diseases in animals, promotion of animal growth, and feed efficiency. However, the scientific literature has indicated the possible presence of antimicrobial drug residues in animal ...
Marjan Majdinasab+5 more
doaj +1 more source
We report here plastid transformation in sugarcane using biolistic transformation and embryogenesis-based regeneration approaches. Somatic embryos were developed from unfurled leaf sections, containing preprogrammed progenitor cells, to recover ...
Ghulam Mustafa, Muhammad Sarwar Khan
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This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
DETERMINATION OF PATHOGEN RESISTANCE TO STREPTOMYCIN
This research was made in order to emphasize the actual incindence of the sensibility of various bacterial pathogens to streptomycin. The pathogens were identified as belonging to Staphylococcus, Escherichia, Citrobacter, Enterobacter, Klebsiella,
Anca CHEREJI, Rareş CHEREJI
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Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink+6 more
wiley +1 more source