Results 21 to 30 of about 18,167 (294)

Wound Healing Activity of the Flavonoid-Enriched Fraction of Selaginella bryopteris Linn. against Streptozocin-Induced Diabetes in Rats

Separations, 2023
Diabetes and its complications, such as delayed wound healing, are increasing at an alarming rate in India, putting an enormous strain on the country’s limited healthcare resources.
Arti Gautam, Vikas Kumar, Lubna Azmi, Ch. V. Rao, Mohammed Moizuddin Khan, Beenish Mukhtar, Mehnaz Kamal, Muhammad Arif, Seema Mehdi, Saud M. Alsanad, Osama A. Al-Khamees, Talha Jawaid, Aftab Alam   +12 more
doaj   +1 more source

Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice

Cells, 2021
The nutrient-sensor O-GlcNAc transferase (Ogt), the sole enzyme that adds an O-GlcNAc-modification onto proteins, plays a critical role for pancreatic β-cell survival and insulin secretion.
Ramkumar Mohan, Seokwon Jo, Elina Da Sol Chung, Eunice Oribamise, Amber Lockridge, Juan E. Abrahante-Lloréns, Hai-Bin Ruan, Xiao-Yong Yang, Emilyn U. Alejandro   +8 more
doaj   +1 more source

Antihyperglycemic and Lipid Profile Effects of Salvia amarissima Ortega on Streptozocin-Induced Type 2 Diabetic Mice

Molecules, 2021
Salvia amarissima Ortega was evaluated to determinate its antihyperglycemic and lipid profile properties. Petroleum ether extract of fresh aerial parts of S.
J. Solares-Pascasio, G. Ceballos, F. Calzada, Elizabeth Barbosa, C. Velázquez   +4 more
semanticscholar   +1 more source

Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Mesenchymal stem cell (MSC) transplantation represents a promising approach for treating Alzheimer’s disease (AD). These stem cells, however, have a short lifespan following transplantation into recipient animals.
Siamak Shahidi, Sara Soleimani Asl, Bahareh Gholamigeravand, Simimn Afshar, Nasrin Hashemi-Firouzi, Alireza Samzadeh-Kermani, Mahsa Majidi, Kimia Amiri   +7 more
doaj   +1 more source

STAT3 dictates β-cell apoptosis by modulating PTEN in streptozocin-induced hyperglycemia [PDF]

Cell Death and Differentiation, 2019
Qinjie Weng, Mengting Zhao, Jiahuan Zheng, Lijun Yang, Zijie Xu, Zhikang Zhang, Jincheng Wang, Jiajia Wang, Bo Yang, Q. Richard Lu, Meidan Ying, Qiaojun He   +11 more
openalex   +2 more sources

Treatment options for PNET liver metastases. a systematic review [PDF]

, 2018
Pancreatic neuroendocrine tumors (PNETs) are rare pancreatic neoplasms. About 40-80% of patients with PNET are metastatic at presentation, usually involving the liver (40-93%). Liver metastasis represents the most significant prognostic factor.
Aurello, Paolo, Crovetto, Anna, Debs, Tarek, Mangogna, Livia Maria, Moschetta, Giovanni, Nigri, Giuseppe, Persechino, Raffaello, Petrucciani, Niccolò, Ramacciato, Giovanni   +8 more
core   +1 more source

Effects of artemisinin and TSP‑1‑human endometrial‑derived stem cells on a streptozocin‑induced model of Alzheimer's disease and diabetes in Wistar rats.

Acta Neurobiologiae Experimentalis, 2021
Alzheimer's disease (AD) is an age‑associated dementia disorder characterized by Aβ plaques and neurofibrillary tangles. There is a strong link between cerebrovascular angiopathy, oxidative stress, inflammation, and glucose metabolism abnormalities with ...
Parvin Poorgholam, P. Yaghmaei, M. Noureddini, Z. Hajebrahimi   +3 more
semanticscholar   +1 more source

Targeting Oxidative Stress and Apoptosis via PI3K/Akt/Nrf2 Pathway: The Therapeutic Role of Bletilla striata Polysaccharide in Diabetic Wound Repair [PDF]

Journal of Diabetes Research
Background Diabetic wounds are challenging and lack efficient therapeutic solutions. Bletilla striata polysaccharide (BSP) has garnered interest for its bioactivity and antioxidant ability in wound healing. This research explores the mechanisms through which BSP alleviates oxidative stress (OS) in L929 cells and prevents cell apoptosis under high ...
Xu S, Ni Z, Zhang T, Zhang X, Li X, Bai L, Yu L, Xu G.   +7 more
europepmc   +2 more sources

Effect of Combined Leaf Extracts of Vernonia amygdalina (Bitter Leaf) and Gongronema latifolium (Utazi) on the Pancreatic beta-Cells of Streptozotocin- Induced Diabetic Rats [PDF]

, 2011
The study evaluated the effect of combined extracts of Vernonia amygdalina (VA) and Gongronema latifolium (GL) on the pancreas of streptozotocin (STZ) induced diabetic Wistar rats. Thirty-two (32) albino rats were divided equally into 4 groups.
Akpantah, Amabe, Akpaso, Mfon I, Atangwho, Item J, Ebong, Patrick E, Fischer, Victor A, Igiri, Anozeng O.   +5 more
core   +1 more source

In vitro & In vivo Phytochemical Evaluation of Bioactive Components Against Hyperglycemic-induced Oxidative Stress in Streptozocin Rat Model: A histopathological investigation

Biointerface Research in Applied Chemistry, 2021
The in vitro antidiabetic and antioxidant potential of Punica granatum, Eriobotrya japonica, and Musa acuminata leaves were evaluated using normal and streptozocin (STZ) induced diabetic rats.
A. Nazir, Rahat Mustafa, M. Iqbal
semanticscholar   +1 more source