Results 11 to 20 of about 8,719 (217)

Successful Salvage Chemotherapy with Streptozocin in a Patient with Mediastinal Atypical Carcinoid Tumor Who Had Relapsed after Various Prior Therapies [PDF]

Case Reports in Oncology, 2018
Pulmonary neuroendocrine tumors are rare, and there have been very few reports regarding optimal chemotherapeutic regimens. Two molecular targeted agents, everolimus and sunitinib, have recently been shown to provide an additional treatment benefit for ...
Toshirou Fukushima, Daisuke Gomi, Noriko Seno, Takahiko Gibo, Takashi Kobayashi, Nodoka Sekiguchi, Hirohide Matsushita, Yoshiko Kasahara, Keiko Mamiya, Tomonobu Koizumi   +9 more
doaj   +3 more sources

Comparative evaluation of pancreatic histopathology of rats treated with olanzapine, risperidone and streptozocin

Brazilian Journal of Pharmaceutical Sciences, 2018
Olanzapine and risperidone are widely prescribed atypical antipsychotics used in the treatment of schizophrenia and various other psychiatric disorders. Both of these drugs have been extensively reported to cause Type 2 diabetes mellitus and pancreatitis,
Rehmat Shah, Fazal Subhan, Sayed Mohammad Sultan, Gowhar Ali, Ihsan Ullah, Sami Ullah   +5 more
doaj   +2 more sources

Ulogata na endoetelin-1 vo razvojot na dijabeticna nefropatija inducirana so streptozocin [PDF]

Makedonsko Farmacevtski Bilten, 2006
Dijabeticnata nefropatija pretstavuva edna od hronicnite mikrovaskularni komplikacii na dijabetot, so multifaktorijalna i ne do kraj rasvetlena etiopatogeneza.
Jasmina Trojacanec, Dimce Zafirov, Maja Slaninka-Miceska, Nikola Labacevski, Elena Kostova, Kalina Gjorgievska, Petar Milosevski, Stojmir Petrov   +7 more
doaj   +1 more source

Capsaicin Mitigates Insulin Resistance-Driven Prostate Hyperplasia Via IGF-1 Signalling Modulation in HFD + STZ Rat Model. [PDF]

J Biochem Mol Toxicol
High‐fat diet with streptozotocin induced Insulin Resistance (IR) with elevated fasting blood glucose, insulin levels and increased Prostate weight. Capsaicin administration significantly ameliorated fasting glucose, insulin levels, reduced prostate weight and downregulated IGF‐1, MEK and ERK expression, and mitigated histopathological alterations ...
Kotaru M, Ranjan Das N.
europepmc   +2 more sources

Responses to medical treatment in patients with metastatic unresectable small intestinal neuroendocrine tumors - A single center study of 378 patients. [PDF]

J Neuroendocrinol
Abstract Small intestinal neuroendocrine tumors (siNET) are rare malignancies, often diagnosed at advanced stages with metastatic spread. While surgery is the only curative treatment, medical therapies, including somatostatin analogues (SSA), peptide receptor radionuclide therapy (PRRT), and other systemic treatments, are essential for disease ...
Slott C, Langer SW, Oturai P, Møller S, Hansen CP, Kjaer A, Holmager P, Klose M, Garbyal RS, Knigge U, Andreassen M.   +10 more
europepmc   +2 more sources

CircRbfox1 Contributes to Colonic Hypersensitivity in Rats With Diabetes by Altering HuC Subcellular Localization to Regulate RBFOX1 Expression. [PDF]

CNS Neurosci Ther
circRbfox1 mediates diabetic colonic hypersensitivity by binding the RNA‐binding protein HuC, facilitating its nuclear translocation in T13‐L2 DRGs. This enhances transcription of the parent gene Rbfox1, culminating in increased expression of the L‐type calcium channel Cav1.3.
Zhang S, Hu J, Ni C, Zhang Y, Chen J, Liu Y, Hu S, Zhang F, Xu GY, Zhang HH.   +9 more
europepmc   +2 more sources

Conventional Transarterial Chemo embolization Using Streptozocin in Patients with Unresectable Neuroendocrine Liver Metastases

, 2023
CERVOXY CLINInternational audienceBackground: The purpose of this study was to evaluate the clinical, biological and radiological responses to, and tolerability of, conventional transarterial chemoembolization (cTACE) using streptozocin for unresectable ...
Alvès, Arnaud, Pasik, Christophe, Arnaud Alvès, Fohlen, Audrey, Audrey Fohlen, Pelage, Jean-Pierre, Christophe Pasik, Remi Beaudouin, Jean-Pierre Pelage, Bouhier-Leporrier, Karine, Karine Bouhier-Leporrier, Beaudouin, Remi   +11 more
core   +1 more source

Effect of Combined Leaf Extracts of Vernonia amygdalina (Bitter Leaf) and Gongronema latifolium (Utazi) on the Pancreatic beta-Cells of Streptozotocin- Induced Diabetic Rats [PDF]

, 2011
The study evaluated the effect of combined extracts of Vernonia amygdalina (VA) and Gongronema latifolium (GL) on the pancreas of streptozotocin (STZ) induced diabetic Wistar rats. Thirty-two (32) albino rats were divided equally into 4 groups.
Igiri, Anozeng O., Fischer, Victor A, Akpaso, Mfon I, Akpantah, Amabe, Ebong, Patrick E, Atangwho, Item J   +5 more
core   +1 more source

Effect of mesenchymal stem cells and polyvinyl alcohol-coated selenium nanoparticles on rats with Alzheimer-like phenotypes [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Mesenchymal stem cell (MSC) transplantation represents a promising approach for treating Alzheimer’s disease (AD). These stem cells, however, have a short lifespan following transplantation into recipient animals.
Siamak Shahidi, Sara Soleimani Asl, Bahareh Gholamigeravand, Simimn Afshar, Nasrin Hashemi-Firouzi, Alireza Samzadeh-Kermani, Mahsa Majidi, Kimia Amiri   +7 more
doaj   +1 more source

Streptozotocin - an antibiotic used to induce diabetes on experimental animals

Journal of Education, Health and Sport, 2020
Streptozotocin (STZ) is a cytostatic antibiotic produced by Streptomyces achromogenes. It is an inhibitor of DNA replication showing a special affinity for pancreatic β-cells DNA.
Dagna Siedlecka, Wojciech Micał, Ewa Krzewicka-Romaniuk   +2 more
doaj   +1 more source