Results 71 to 80 of about 18,167 (294)

Hypoglycemic, hypolipidemic and antioxidant effects of iridoid glycosides extracted from: Corni fructus: Possible involvement of the PI3K-Akt/PKB signaling pathway [PDF]

, 2018
Iridoid glycosides (CIG) are the major component of Corni fructus. In this work, we researched the antioxidative, hypoglycemic and lowering blood lipids effects of CIG on diabetic mice induced by a high-fat diet (HFD) and streptozotocin (STZ ...
Cao, Xiaoyan, Guo, Chen, Kang, Jiefang, Li, Xing, Thome, Rodolfo, Yang, Ning, Zhang, Yuan   +6 more
core   +2 more sources

Lannea coromandelica (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam, Sumaya Akter, Anika Rahman, Taniza Tasnim, Md. Mhamudul Huda Ruhed, Anika Ahmed, Naznin Rahman, Afsana Akter Mim, Tasnim Tabassum, Md. Mazharul Islam Chowdhury, Jakir Ahmed Chowdhury   +10 more
wiley   +1 more source

The long-acting somatostatin analogue octreotide alleviates symptoms by reducing posttranslational conversion of prepro-glucagon to glucagon in a patient with malignant glucagonoma, but does not prevent tumor growth [PDF]

, 1994
A 52-year-old female with metastatic glucagonoma secreting glucagon and chromogranin A was treated with the somatostatin analogue octreotide for 2 years without any additional tumor-reducing interventions. Before therapy plasma glucagon was above 8 μg/l (
Jockenhövel, F. (F.), Krenning, E.P. (Eric), Lamberts, S.W.J. (Steven), Lederbogen, S. (S.), Olbricht, T. (T.), Reinwein, D. (D.), Schmidt-Gayk, H. (H.)   +6 more
core   +2 more sources

Somatostatin analogs in neuroendocrine tumors with Ki‐67 index of ≥10%

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Somatostatin analogs (SSAs) are an established first‐line therapy in intestinal and pancreatic neuroendocrine tumors (NETs). Based on Phase III studies, their use is recommended in NET with a Ki‐67 index of up to 10%. The effect of first‐line SSA therapy on differentiated NET with a Ki‐67 index ≥10% is poorly understood.
Johanna Braegelmann, Annie Mathew, Boerge Schmidt, Hamza Kalisch, Wolfgang P. Fendler, Dagmar Führer‐Sakel, Harald Lahner   +6 more
wiley   +1 more source

The effects of crocin on the serum levels of sex hormone and NO in streptozotocin – induced diabetic rats.

مجله علمی دانشگاه علوم پزشکی کردستان, 2018
Background and Aim: Diabetes can lead to reduced fertility in men by production of free radicals. Crocin (the effective component of saffron) with its antioxidant property can be effective in elimination of free radicals.
Hananeh Bahojb Soldozi, Faramarz Jalili, Maryam Sohrabi, Zahra Keshtmand, Cyrus Jalili   +4 more
doaj  

Comparative evaluation of pancreatic histopathology of rats treated with olanzapine, risperidone and streptozocin

Brazilian Journal of Pharmaceutical Sciences, 2018
Olanzapine and risperidone are widely prescribed atypical antipsychotics used in the treatment of schizophrenia and various other psychiatric disorders. Both of these drugs have been extensively reported to cause Type 2 diabetes mellitus and pancreatitis,
Rehmat Shah, Fazal Subhan, Sayed Mohammad Sultan, Gowhar Ali, Ihsan Ullah, Sami Ullah   +5 more
doaj   +1 more source

Antidiabetic Effect of Collagen Peptides from Harpadon nehereus Bones in Streptozotocin-Induced Diabetes Mice by Regulating Oxidative Stress and Glucose Metabolism

Marine Drugs, 2023
Oxidative stress and abnormal glucose metabolism are the important physiological mechanisms in the occurrence and development of diabetes. Antioxidant peptides have been reported to attenuate diabetes complications by regulating levels of oxidative ...
Qianxia Lin, Yueping Guo, Jie Li, Shuqi He, Yan Chen, Huoxi Jin   +5 more
doaj   +1 more source

The Effect of Chlorella vulgaris Supplementation on Liver Enzymes, Serum Glucose and Lipid Profile in Patients with Non-Alcoholic Fatty Liver Disease [PDF]

, 2014
Background: Non-alcoholic fatty liver disease (NAFLD) is becoming a public health problem worldwide and using microalgae is a new approach on its treatment.
Mehrangiz Ebrahimi-Mameghani, Mohammad AsghariJafarabadi, Soodabeh Aliashrafi, Yousef Javadzadeh   +3 more
core   +1 more source

The influence of anberr-antitox and silymarin on oxidative phosphorilation and lipid peroxide oxidation in rat’s liver in the experimental diabetes mellitus

Бюллетень сибирской медицины, 2006
The model of diabetes mellitus caused by intraperitoneal injection of streptozotocin in dose of 65 mg/kg in experiment on rats was accompanied by alternation of mitochondrial functions (hyperactivation of respiration and disconnection of oxidative ...
K. A. Eskina, K. Yu. Vasilyev
doaj   +1 more source

Comparative Study of Hypoglycemic Effects and Mechanisms of Crude and Wine‐Processed Polysaccharides From Polygonatum sibiricum

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
PSPC and PSPW can decrease the GOD activity and reduce ROS levels in the oxidative stress injury model of HepG2 cells. PSPC and PSPW can improve T2DM by regulating oxidative and insulin signaling pathway. PSPW has better therapeutic effect on T2DM than PSPC. ABSTRACT Polygonatum sibiricum (PS), a traditional food and medicinal plant, primarily consists
Hui Yang, Shuhua Zhao, Zhuoke Li, Junfeng Liu, Yang Liu, Wenbing Zhi, Hong Zhang, Tingting Sun   +7 more
wiley   +1 more source