Results 71 to 80 of about 13,291 (204)

A Case of Streptozocin Monotherapy for Unresectable Duodenal Neuroendocrine Tumor G2

open access: yesCase Reports in Oncology, 2019
Background: Duodenal neuroendocrine tumors (NET) are rare, and few reports have demonstrated the effectiveness of chemotherapy for duodenal NET, with not many other treatment options available. Here, we present a case of unresectable duodenal NET G2 that
Koji Miyagawa   +4 more
doaj   +1 more source

Crystal Structure of Streptozocin

open access: yesAnalytical Sciences: X-ray Structure Analysis Online, 2003
The crystal belongs to space group P212121, and the cell dimensions are a = 8.5300(5), b = 11.4516(9) and c = 23.893(1)A. The final R value is 0.047. There are two crystallographically independent molecules in an asymmetric unit. The pyranose rings in both molecules take chair conformations. The nitrosourea moieties are planar.
Masayuki HARAMURA   +3 more
openaire   +2 more sources

Gestational diabetes induces neuronal loss in dentate gyrus in rat offspring [PDF]

open access: yes, 2014
Background: This study was conducted to determine the effect of gestational diabetes on neuronal density in the dentate gyrus (DG) subfields of hippocampus in rats offspring. Methods: On day 1 of gestation, 10 dams randomly allocated into two control and
Ghafari, S.   +2 more
core  

Comparative Study of Hypoglycemic Effects and Mechanisms of Crude and Wine‐Processed Polysaccharides From Polygonatum sibiricum

open access: yesFood Science &Nutrition, Volume 13, Issue 12, December 2025.
PSPC and PSPW can decrease the GOD activity and reduce ROS levels in the oxidative stress injury model of HepG2 cells. PSPC and PSPW can improve T2DM by regulating oxidative and insulin signaling pathway. PSPW has better therapeutic effect on T2DM than PSPC. ABSTRACT Polygonatum sibiricum (PS), a traditional food and medicinal plant, primarily consists
Hui Yang   +7 more
wiley   +1 more source

Evaluation of blood sugar lowering effect of airy organs extract of Cupressus sempervirens L. on streptozocin induced diabetic mice

open access: yesمجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Cupressus extract has been considered as antioxidant and free radical scavenger. In this study we evaluated the effect of hydroalcoholic extract of Cupressus sempervirens L.
Fatemeh Shaki   +3 more
doaj  

Quantitative studies of hepatocytes in periportal and perivenous zones of the liver lobules in diabetic rats [PDF]

open access: yes, 2007
This study was designed to evaluate the morphometric changes of parenchymal cells in the periportal (Z1) and perivenous (Z3) zones of the liver lobules that occur after Streptozotocin-induced diabetes in rats.
Ghafari, S., Golalipour, M.J.
core  

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

open access: yesChemMedChem, Volume 20, Issue 18, September 25, 2025.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali   +7 more
wiley   +1 more source

Evaluation of the effects of new peptide compounds in experimental animals with a toxic model of Alzheimer’s disease

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Development of new approaches to the treatment of Alzheimersdisease (AD) is an actual problem of modern neurology owingto high prevalence of AD in the population and severe irreversibledisability resulting from this disease. We investigated the effectsof
A. V. Stavrovskaya   +4 more
doaj   +1 more source

Pharmacological Activities of Boswellia serrata Roxb. - Mini Review [PDF]

open access: yes, 2009
Boswellia serrata (Salai Guggal) is one of the most ancient and respected herbs in Ayurveda. “Gajabhakshya” a Sanskrit name sometimes used for Boswellia suggests that elephants enjoy this herb as a part of their diet.
Ghule, Balu, Upaganlawar, Aman
core   +1 more source

Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

open access: yesAdvanced Science, Volume 12, Issue 35, September 18, 2025.
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy