Results 71 to 80 of about 13,291 (204)
A Case of Streptozocin Monotherapy for Unresectable Duodenal Neuroendocrine Tumor G2
Background: Duodenal neuroendocrine tumors (NET) are rare, and few reports have demonstrated the effectiveness of chemotherapy for duodenal NET, with not many other treatment options available. Here, we present a case of unresectable duodenal NET G2 that
Koji Miyagawa +4 more
doaj +1 more source
Crystal Structure of Streptozocin
The crystal belongs to space group P212121, and the cell dimensions are a = 8.5300(5), b = 11.4516(9) and c = 23.893(1)A. The final R value is 0.047. There are two crystallographically independent molecules in an asymmetric unit. The pyranose rings in both molecules take chair conformations. The nitrosourea moieties are planar.
Masayuki HARAMURA +3 more
openaire +2 more sources
Gestational diabetes induces neuronal loss in dentate gyrus in rat offspring [PDF]
Background: This study was conducted to determine the effect of gestational diabetes on neuronal density in the dentate gyrus (DG) subfields of hippocampus in rats offspring. Methods: On day 1 of gestation, 10 dams randomly allocated into two control and
Ghafari, S. +2 more
core
PSPC and PSPW can decrease the GOD activity and reduce ROS levels in the oxidative stress injury model of HepG2 cells. PSPC and PSPW can improve T2DM by regulating oxidative and insulin signaling pathway. PSPW has better therapeutic effect on T2DM than PSPC. ABSTRACT Polygonatum sibiricum (PS), a traditional food and medicinal plant, primarily consists
Hui Yang +7 more
wiley +1 more source
Background and Aim: Cupressus extract has been considered as antioxidant and free radical scavenger. In this study we evaluated the effect of hydroalcoholic extract of Cupressus sempervirens L.
Fatemeh Shaki +3 more
doaj
Quantitative studies of hepatocytes in periportal and perivenous zones of the liver lobules in diabetic rats [PDF]
This study was designed to evaluate the morphometric changes of parenchymal cells in the periportal (Z1) and perivenous (Z3) zones of the liver lobules that occur after Streptozotocin-induced diabetes in rats.
Ghafari, S., Golalipour, M.J.
core
Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali +7 more
wiley +1 more source
Development of new approaches to the treatment of Alzheimersdisease (AD) is an actual problem of modern neurology owingto high prevalence of AD in the population and severe irreversibledisability resulting from this disease. We investigated the effectsof
A. V. Stavrovskaya +4 more
doaj +1 more source
Pharmacological Activities of Boswellia serrata Roxb. - Mini Review [PDF]
Boswellia serrata (Salai Guggal) is one of the most ancient and respected herbs in Ayurveda. “Gajabhakshya” a Sanskrit name sometimes used for Boswellia suggests that elephants enjoy this herb as a part of their diet.
Ghule, Balu, Upaganlawar, Aman
core +1 more source
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen +17 more
wiley +1 more source

