Results 81 to 90 of about 18,167 (294)

Very low doses of muscimol and baclofen ameliorate cognitive deficits and regulate protein expression in the brain of a rat model of streptozocin-induced Alzheimer's disease

open access: greenEuropean Journal of Pharmacology, 2017
Vladimirs Piļipenko   +6 more
openalex   +3 more sources

Effect of Diabetes on Median and Dorsal Raphe Nuclei Efferent Fibers to CA3 Hippocampal Area in Rat

open access: yesActa Medica Iranica, 2010
Diabetes Mellitus (DM) is one of the most important metabolic disease causes in many side effects. The decrease of mental abilities and even some form of dementia followed prolonged diabetes has been reported.
Gholamreza Hassanzadeh   +4 more
doaj  

Brown adipose tissue uptake of triglyceride-rich lipoprotein-derived fatty acids in diabetic or obese mice under different temperature conditions

open access: yesEJNMMI Research, 2020
Background In vivo imaging of glucose analogue 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) via positron emission tomography (PET) is the current gold standard to visualize and assess brown adipose tissue (BAT) activity. However, glucose metabolism is only
Andreas Paulus   +4 more
doaj   +1 more source

Seasonal Variation in Leaf Growth and Antioxidant Content of Moringa oleifera Cultivated at Buenos Aires, Argentina [PDF]

open access: yes, 2016
The properties and applications of Moringa oleifera are so vast that it is called the "miracle tree". The objective of this work is to study the seasonal variations in the leaf antioxidant content and the scavenging activity on DPPH radicals in ...
Arena, Miriam Elisabet, Radice, Silvia
core   +1 more source

Study on the Antidiabetic Effect of Carbon Tetrachloride Extract of Trigonella Foenum Seed in Streptozocin Induced Diabetic Rats

open access: yesپزشکی بالینی ابن سینا, 2005
Introduction & Objective : Diabetes mellitus is a disease with a long history. Attempts to relieve the symptoms have not been totally successful. The seeds of Trigonella foenum have been shown to possess hypoglycemic properties.
Saleh Zahedi Asl, Behzad Zaree
doaj  

Gestational diabetes induces neuronal loss in dentate gyrus in rat offspring [PDF]

open access: yes, 2014
Background: This study was conducted to determine the effect of gestational diabetes on neuronal density in the dentate gyrus (DG) subfields of hippocampus in rats offspring. Methods: On day 1 of gestation, 10 dams randomly allocated into two control and
Ghafari, S.   +2 more
core  

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

open access: yesChemMedChem, Volume 20, Issue 18, September 25, 2025.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali   +7 more
wiley   +1 more source

IMMUNOLOGIC PREVENTION OF IDDM BY ORAL ADMINISTRATION OF GLUTAMIC ACID DECARBOXYLASE [PDF]

open access: yesActa Medica Iranica, 1999
We have Investigated the preventive effects of oral administration of isolated E.coli ghttam'tc acid decarboxylase (GAD) in animal models. Based on our results, the blood glucose levels were reduced by oral administration of GAD to rats 14 days before ...
L. Yazdchi Mari   +1 more
doaj   +1 more source

A Case of Streptozocin Monotherapy for Unresectable Duodenal Neuroendocrine Tumor G2

open access: yesCase Reports in Oncology, 2019
Background: Duodenal neuroendocrine tumors (NET) are rare, and few reports have demonstrated the effectiveness of chemotherapy for duodenal NET, with not many other treatment options available. Here, we present a case of unresectable duodenal NET G2 that
Koji Miyagawa   +4 more
doaj   +1 more source

Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

open access: yesAdvanced Science, Volume 12, Issue 35, September 18, 2025.
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen   +17 more
wiley   +1 more source

Home - About - Disclaimer - Privacy