Results 71 to 80 of about 13,379 (221)

A Case of Streptozocin Monotherapy for Unresectable Duodenal Neuroendocrine Tumor G2

Case Reports in Oncology, 2019
Background: Duodenal neuroendocrine tumors (NET) are rare, and few reports have demonstrated the effectiveness of chemotherapy for duodenal NET, with not many other treatment options available. Here, we present a case of unresectable duodenal NET G2 that
Koji Miyagawa, Yudai Nakabayashi, Yosuke Ishihara, Momoko Todo, Nobuaki Fuji   +4 more
doaj   +1 more source

Indications for Surgical Resection in Patients With Neuroendocrine Tumor Liver Metastases: An Intensive Surgical Experience of a High‐Volume Center

Annals of Gastroenterological Surgery, Volume 10, Issue 1, Page 219-228, January 2026.
In patients with NELM, those with < 8 liver metastases and G1/2 tumors are the favorable candidates for liver resection. The important point of this study is that the patients who do not meet the above criteria should be considered for multidisciplinary treatment because of their extremely shorter recurrence‐free period.
Daisuke Asano, Toshitaka Sugawara, Keiichi Akahoshi, Shotaro Gan, Shohei Motohashi, Shuichi Watanabe, Yoshiya Ishikawa, Hiroki Ueda, Atsushi Kudo, Daisuke Ban   +9 more
wiley   +1 more source

Evaluation of blood sugar lowering effect of airy organs extract of Cupressus sempervirens L. on streptozocin induced diabetic mice

مجله علمی دانشگاه علوم پزشکی کردستان, 2019
Background and Aim: Cupressus extract has been considered as antioxidant and free radical scavenger. In this study we evaluated the effect of hydroalcoholic extract of Cupressus sempervirens L.
Fatemeh Shaki, Emran Habibi, Masood Paran Davaji, Ramin Ataee   +3 more
doaj  

Evaluation of the leaves of Ipomoea aquatica for its hypoglycemic and antioxidant activity [PDF]

, 2011
The present study was accomplished to explore the hypoglycemic and antioxidant activity of methanolic extracts of the leaves of I.aquatica. The animals used to test the antidiabetic activity were Swiss albino mice of 7-8 weeks, average weight 20-30 gm of
Basak, Debasish, Hamid, Kaiser, Howlader, Md. Amran, Nasrin, Fatema, Rahman, Muhammad Mukhlesur, Sultana, Shapna, Ullah, Mohammad Obayed   +6 more
core  

Anti‐Diabetic Effects of Ayanin, a Flavonoid Compound, in STZ/HFD‐Induced Diabetic Mice by Upregulating GLUT4 and Suppressing Macrophage‐Driven Inflammation in Adipose Tissues

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Ayanin, a flavonoid extracted from red wine grapes, has demonstrated efficacy in ameliorating hyperglycemia, dyslipidemia, and insulin resistance through directly targeting the AMPKα/GLUT4 and AMPKα/CPT‐1α signaling pathways in metabolic tissues.
Yibing Lv, Chunyu Wu, Wenke Yang, Chenyang Wang, Jianmei Huang, Jinming Wang, XiaoLiang Xia, Dong Wu, Ke Yang, Zhenglong Guo, Shixiu Liao   +10 more
wiley   +1 more source

The long-acting somatostatin analogue octreotide alleviates symptoms by reducing posttranslational conversion of prepro-glucagon to glucagon in a patient with malignant glucagonoma, but does not prevent tumor growth [PDF]

, 1994
A 52-year-old female with metastatic glucagonoma secreting glucagon and chromogranin A was treated with the somatostatin analogue octreotide for 2 years without any additional tumor-reducing interventions. Before therapy plasma glucagon was above 8 μg/l (
Jockenhövel, F. (F.), Krenning, E.P. (Eric), Lamberts, S.W.J. (Steven), Lederbogen, S. (S.), Olbricht, T. (T.), Reinwein, D. (D.), Schmidt-Gayk, H. (H.)   +6 more
core   +2 more sources

Lannea coromandelica (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam, Sumaya Akter, Anika Rahman, Taniza Tasnim, Md. Mhamudul Huda Ruhed, Anika Ahmed, Naznin Rahman, Afsana Akter Mim, Tasnim Tabassum, Md. Mazharul Islam Chowdhury, Jakir Ahmed Chowdhury   +10 more
wiley   +1 more source

Gestational diabetes induces neuronal loss in dentate gyrus in rat offspring [PDF]

, 2014
Background: This study was conducted to determine the effect of gestational diabetes on neuronal density in the dentate gyrus (DG) subfields of hippocampus in rats offspring. Methods: On day 1 of gestation, 10 dams randomly allocated into two control and
Ghafari, S., Golalipour, M.J., Kafshgiri, S.K.   +2 more
core  

Stimulation of glucose utilization in 3T3 adipocytes and rat diaphragm in vitro by the sulphonylureas, glimepiride and glibenclamide, is correlated with modulations of the cAMP regulatory cascade [PDF]

, 1994
The long-term hypoglycemic activity of sulphonylurea drugs has been attributed, in part at least, to the stimulation of glucose utilization in extra-pancreatic tissues. The novel sulphonylurea, glimepiride, gives rise to a longer lasting reduction in the
Altan, Aoki, Avruch, Bak, Begum, Brown, Caren, Clancy, Cooper, Cushman, Daniels, Davidson, Farese, Feldman, Feldman, Gavin, Geisen, Gould, Guinovart, Hirshman, Honnor, Jacobs, Jacobs, Jacobs, James, James, Karnieli, Kirsch, Klip, Kolterman, Kono, Lane, Larner, Lawrence, Lawson, Lebovitz, Leichter, Maloff, Mandarino, Misek, Moody, Müller, Müller, Müller, Müller, Müller, Okuno, Oron, Osegawa, Panten, Popov, Putnam, Reusch, Rogers, Roskoski, Saltiel, Saltiel, Saltiel, Simonson, Smith, Solomon, Standing, Suissa, Suzuki, Tordjman, Towbin, Van Putten, Vila, Villalba, Wang, Wang, Wieland, Wray, Yalow, Zinman, Zuber   +75 more
core   +1 more source

Somatostatin analogs in neuroendocrine tumors with Ki‐67 index of ≥10%

Journal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Somatostatin analogs (SSAs) are an established first‐line therapy in intestinal and pancreatic neuroendocrine tumors (NETs). Based on Phase III studies, their use is recommended in NET with a Ki‐67 index of up to 10%. The effect of first‐line SSA therapy on differentiated NET with a Ki‐67 index ≥10% is poorly understood.
Johanna Braegelmann, Annie Mathew, Boerge Schmidt, Hamza Kalisch, Wolfgang P. Fendler, Dagmar Führer‐Sakel, Harald Lahner   +6 more
wiley   +1 more source