Results 11 to 20 of about 188,322 (318)

Effect of tyrosine protein kinase blockade on the state of retinal microglia in diabetic retinopathy

Mìžnarodnij Endokrinologìčnij Žurnal, 2023
Background. Impaired homeostasis of the retinal tissue in diabetes primarily involves microglia, which triggers a cascade of inflammatory reactions, one of the main mechanisms of diabetic retinopathy (DR).
V.V. Vodianyk, S.V. Ziablitzev, V.I. Andrushchenko   +2 more
doaj   +1 more source

Streptozotocin‐Induced Diabetic Models in Mice and Rats

Current Protocols, 2021
Streptozotocin (STZ) is an antibiotic that causes pancreatic islet β‐cell destruction and is widely used experimentally to produce a model of type 1 diabetes mellitus (T1DM).
B. Furman
semanticscholar   +1 more source

State of peroxidation in the brain and liver in experimental diabetes and its correction possibility with niacin-oxyethylendiphosphonatogermanate

Zaporožskij Medicinskij Žurnal, 2023
The development of pharmacological methods to control oxidant stress manifestations in diabetes can be achieved using organic complex germanium compounds.
V. Y. Kresiun, N. Al-Nadawi Javad
doaj   +1 more source

Streptozotocin, 1982–2022: Forty Years from the FDA’s Approval to Treat Pancreatic Neuroendocrine Tumors

Neuroendocrinology, 2022
In May 1982, the US Food and Drug Administration (FDA) approved the use of streptozotocin to treat pancreatic neuroendocrine tumors (panNETs). Thus, this year marks 40 years since that landmark date.
J. Capdevila, M. Ducreux, R. García Carbonero, E. Grande, T. Halfdanarson, M. Pavel, S. Tafuto, S. Welin, V. Valentí, R. Salazar   +9 more
semanticscholar   +1 more source

HYPOGLYCEMIC EFFECT OF SITAGLIPTIN AND AMINOGUANIDINE COMBINATION IN EXPERIMENTAL DIABETES MELLITUS

Фармация и фармакология (Пятигорск), 2023
The aim of the work was to determine the antidiabetic effect of a sitagliptin and aminoguanidine combination in rats with experimental diabetes mellitus.Materials and methods.
D. V. Kurkin, D. A. Bakulin, E. I. Morkovin, Yu. V. Gorbunova, A. V. Strygin, T. M. Andriashvili, A. A. Sokolova, N. S. Bolokhov, V. E. Pustynnikov, E. A. Fomichev   +9 more
doaj   +1 more source

Morchella esculenta mushroom polysaccharide attenuates diabetes and modulates intestinal permeability and gut microbiota in a type 2 diabetic mice model

Frontiers in Nutrition, 2022
Type 2 diabetes mellitus (T2DM) is a health issue that causes serious worldwide economic problems. It has previously been reported that natural polysaccharides have been studied with regard to regulating the gut microbiota, which plays an important role ...
Ata Ur Rehman, Nimra Zafar Siddiqui, Nabeel Ahmed Farooqui, Gulzar Alam, Aneesa Gul, Bashir Ahmad, Muhammad Asim, Asif Iqbal Khan, Yi Xin, Wang Zexu, Hyo Song Ju, Wang Xin, Sun Lei, Liang Wang   +13 more
doaj   +1 more source

Influence of N-acetylcysteine on pituitary-gonadal axis hormones and protamine expression level in streptozotocin-induced diabetic male rats

Asian Pacific Journal of Reproduction, 2020
Objective: To study the influence of N-acetylcysteine on the pituitary-gonadal axis hormones and protamine expression level in streptozotocin-induced diabetic male rats. Methods: Forty-two adult male Wistar rats were divided into 6 groups, with 7 rats in
Maryam Hassanzadeh Moghadam, Mehrdad Shariati, Sirous Naeimi, Mohammad Amin Edalatmanesh   +3 more
doaj   +1 more source

Insights in diabetes: Molecular mechanisms-Protectin DX, an anti-inflammatory and a stimulator of inflammation resolution metabolite of docosahexaenoic acid, protects against the development of streptozotocin-induced type 1 and type 2 diabetes mellitus in male Swiss albino mice

Frontiers in Endocrinology, 2023
Our previous studies revealed that certain endogenous low molecular weight lipids have potent anti-diabetic actions. Of all, arachidonic acid (AA) and its anti-inflammatory and inflammation resolving metabolite lipoxin A4 (LXA4) are the most potent anti ...
Poorani Rengachar, Poorani Rengachar, Sailaja Polavarapu, Sailaja Polavarapu, Undurti N. Das, Undurti N. Das, Undurti N. Das   +6 more
doaj   +1 more source

Triphala Churna—A Traditional Formulation in Ayurveda Mitigates Diabetic Neuropathy in Rats

Frontiers in Pharmacology, 2021
Neuropathy is a common complication of diabetes affecting a large number of people worldwide. Triphala churna is a formulation mentioned in Ayurveda-a traditional system of medicine. It is a simple powder formulation consisting of powders of three fruits,
Sachin V. Suryavanshi, Kalyani Barve, Veeranjaneyulu Addepalli, Sachin V. Utpat, Yogesh A. Kulkarni   +4 more
doaj   +1 more source

LIPID METABOLISM IN DIABETIC RATS AS AFFECTED BY CANOLA AND MUSTARD SEED SPROUTS [PDF]

Arab Universities Journal of Agricultural Sciences, 2018
Canola (Brassica juncea L.) and mustard (Sinapis alba L.) seed sprout effects on diabetic rats  have no available information and to clarify their effects, both sprouts were investigated in streptozotocin (STZ) induced diabetic and normal rats. Rats were
Hanaa Amer, Tahany Aly, K. Tobgy, M. Abdallah, N. El-Shahat   +4 more
doaj   +1 more source