Results 31 to 40 of about 151,903 (303)

Stability of a type 2 diabetes rat model induced by high-fat diet feeding with low-dose streptozotocin injection

Journal of Zhejiang University SCIENCE B, 2018
The present study aims at determining the stability of a popular type 2 diabetes rat model induced by a high-fat diet combined with a low-dose streptozotocin injection.
Xiao-Xuan Guo, Yong Wang, Kai Wang, B. Ji, Feng Zhou   +4 more
semanticscholar   +1 more source

Diabetic alteration versus postnatal maturation of rat kidney glycoconjugates — comparative detection by lectin probes [PDF]

, 2013
A panel of ten lectins with different carbohydrate specificities, including three original lectin preparations (MPFA, LABA, and LVA), was used for the investigation of rat kidney glycoconjugate remodeling during postnatal morphogenesis, and the findings ...
Ambarova, Natalya; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine, Lutsyk, Alexander; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine, Antonyuk, Volodymyr; Department of Histology and Embryology, Lviv National, Medical University, Lviv, Ukraine; Institute of Cell Biology, National Academy of Sciences of Ukraine, Lviv, Ukraine   +2 more
core   +1 more source

Experimental Models of Type 2 Diabetes Mellitus Induced by Combining Hyperlipidemic Diet (HFD) and Streptozotocin Administration in Rats: An Integrative Review

Biomedicines
Type 2 diabetes mellitus (DM2) is a metabolic disorder characterized by chronic hyperglycemia associated with low insulin production and/or insulin resistance.
Ana Karolinne da Silva Brito, Ana Victória da Silva Mendes, Boris Timah Acha, Amanda Suellenn da Silva Santos Oliveira, Joyce Lopes Macedo, Akemi Suzuki Cruzio, Maria das Graças Prianti, R. de Abreu, M. Lucarini, A. Durazzo, Maria Do Carmo de Carvalho e Martins, D. Arcanjo   +11 more
semanticscholar   +1 more source

Anti-Diabetic Effect of Cotreatment with Quercetin and Resveratrol in Streptozotocin-Induced Diabetic Rats

Biomolecules & Therapeutics, 2018
Quercetin and resveratrol are known to have beneficial effects on the diabetes and diabetic complication, however, the effects of combined treatment of these compounds on diabetes are not fully revealed.
D. Yang, Hyung-Sub Kang
semanticscholar   +1 more source

Enrichment of Bioactive Lipids in Urinary Extracellular Vesicles and Evidence of Apoptosis in Kidneys of Hypertensive Diabetic Cathepsin B Knockout Mice after Streptozotocin Treatment

Biomedicines
Cathepsin B (CtsB) is a ubiquitously expressed cysteine protease that plays important roles in health and disease. Urinary extracellular vesicles (uEVs) are released from cells associated with urinary organs.
Whitney C. Schramm, Niharika Bala, Tanmay Arekar, Zeeshan Malik, Kevin M. Chacko, Russell L. Lewis, Nancy D. Denslow, Yogesh Scindia, Abdel A. Alli   +8 more
doaj   +1 more source

Therapeutic Effect of Okra (Abelmoschus esculentus Moench) Pods Extract on Streptozotocin-Induced Type-2 Diabetic Mice

Research Journal of Pharmacy and Technology, 2019
The aims of this study were to determine the effect of various fractions of okra pods extract (VOPE) to the changes of fasting blood glucose, serum insulin, and GLUT4 density on streptozotocin-induced type-2 diabetic mice.
S. A. Husen, A. Ansori, S. Hayaza, R. J. Susilo, A. A. Zuraidah, D. Winarni, H. Punnapayak, W. Darmanto   +7 more
semanticscholar   +1 more source

UHPLC/QTOF-MS-based metabolomics reveal the effect of Melastoma dodecandrum extract in type 2 diabetic rats

Pharmaceutical Biology, 2019
Context: Melastoma dodecandrum Lour. (Melastomataceae) is a traditional Chinese medicine. This is the first study to report a protective effect of the ethanol extract from M. dodecandrum (MDE) in type 2 diabetic (T2DM) rats. Objective: To investigate the
Jingyu Weng, Jingkai Zhou, Liqing Liang, Li Li   +3 more
doaj   +1 more source

A Comprehensive Study of Chronic Diabetes Complications in Streptozotocin-Induced Diabetic Rat

Makara Journal of Health Research, 2016
Background: The purpose of this study was to provide a reference of chronic diabetes complications by investigating the prolonged hyperglycemia effects on hematological, biochemical and histopathological changes (liver, kidney, spleen, cardiac muscle ...
Sinan MA Al-Mahmood, Tariq A. Razak, Shahrin TC Abdullah, Nik N. Fatnoon NA, Abdul H. Mohamed, Imad M. Al-Ani   +5 more
doaj   +1 more source

Renoprotection by Garcinia mangostana L. pericarp extract in streptozotocin-induced diabetic mice

Iraqi Journal of Veterinary Sciences, 2019
The purpose of this study was to evaluate the renoprotective effect of the Garcinia mangostana L. pericarp extract (GMPE) on plasma creatinine and renal proximal tubules of streptozotocin-induced diabetic mice. This study used 36 male Balb/c strain mice.
A. Ansori, Raden Joko Kuncoroningrat Kuncoroningrat Kuncoroningrat, S. Hayaza, D. Winarni, S. A. Husen   +4 more
semanticscholar   +1 more source

Targeting CD300a Signaling With a Phosphatidylserine‐Presenting Hydrogel Rescues Macrophage Dysfunction and Accelerates Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the proposed mechanism: PEG/RGD‐PSLs mimic apoptotic cells to engage PS receptors (notably CD300a), transducing an inhibitory signal that suppresses the MyD88/NF‐κB pathway, leading to global anti‐inflammatory and pro‐reparative effects.
Lele Wu, Xuetong Hao, Yang Zou, Xinglin Chen, Junyan Kong, Chunning Gu, Wenjie Ma, Zhongjun Yang, Huifen Liu, Mengmeng Liu, Xin Tong   +10 more
wiley   +1 more source